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Note 11 - Benefit Plans (Tables)

3 Months Ended

Mar. 31, 2024

Notes Tables

Share-Based Payment Arrangement, Cost by Plan [Table Text Block]

		Three Months Ended March 31,
(in thousands)		2024				2023
General and administrative		$	1,136			$	1,250
Research and development			877				973
Total stock-based compensation expense		$	2,013			$	2,223

		Three Months Ended March 31,
(in thousands)		2024				2023
Stock options		$	2,002			$	2,222
Stock awards			11				1
Total stock-based compensation expense		$	2,013			$	2,223

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

(in thousands, except share, per share, and term data)		Number of Options				Weighted Average Exercise Price Per Share				Weighted Average Remaining Term (Years)				Intrinsic Value
Outstanding – December 31, 2023			21,846,388			$	2.26				7.28			$	302
Granted			280,070				0.44				9.95				—
Forfeited			(141,124	)			5.33				—				—
Outstanding – March 31, 2024			21,985,334			$	2.22				7.07			$	568
Vested and exercisable – March 31, 2024			12,511,524			$	2.55				5.79			$	567
Vested, exercisable or expected to vest – March 31, 2024			21,985,334			$	2.22				7.07			$	568

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Three Months Ended March 31,
		2024				2023
Expected stock price volatility			99.99	%			96.22% –103.24	%
Risk-free interest rate			4.04	%			3.38% –3.98	%
Expected dividend yield			0.00	%			0.00	%
Expected term of options (in years)			5.00				5.00 –6.08

Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]

		Number of Stock Awards				Weighted Average Grant Date Fair Value
Unvested balance – December 31, 2023			778,815			$	9.72
Converted to shares of Common Stock upon vesting			(10,870	)			1.15
Unvested balance – March 31, 2024			767,945			$	9.84

X

- Definition

Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit.

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-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-Publisher FASB
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- Definition

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