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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Cash flows from operating activities:    
Net loss $ (11,080) $ (11,770)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 420 402
Non-cash lease expense 122 108
Commitment share expense (0) 399
Change in fair value of common stock warrant liabilities 1,309 (0)
Change in fair value of Clene Nanomedicine contingent earn-out liability (53) 55
Change in fair value of Initial Stockholders contingent earn-out liability (7) 7
Stock-based compensation expense 2,013 2,223
Accretion of debt discount 367 250
Non-cash interest income on marketable securities (81) 0
Non-cash interest expense on notes payable 91 82
Changes in operating assets and liabilities:    
Accounts receivable 79 126
Inventory 0 (45)
Prepaid expenses and other current assets (428) (581)
Accounts payable 141 (2,406)
Accrued liabilities 185 2,070
Operating lease obligations (160) (138)
Net cash used in operating activities (7,082) (9,218)
Cash flows from investing activities:    
Purchases of marketable securities (6,168) 0
Proceeds from maturities of marketable securities 6,250 5,000
Purchases of property and equipment (11) (278)
Net cash provided by investing activities 71 4,722
Cash flows from financing activities:    
Proceeds from issuance of common stock and warrants, net of offering costs 0 4,266
Payments of finance lease obligations (19) (28)
Proceeds from the issuance of notes payable 0 350
Net cash provided by (used in) financing activities (19) 4,588
Effect of foreign exchange rate changes on cash and restricted cash (59) 18
Net increase (decrease) in cash, cash equivalents and restricted cash (7,089) 110
Cash, cash equivalents and restricted cash – beginning of period 28,879 18,390
Cash, cash equivalents and restricted cash – end of period 21,790 18,500
Reconciliation of cash, cash equivalents and restricted cash to the consolidated balance sheets    
Cash and cash equivalents 21,732 18,442
Restricted cash 58 58
Cash, cash equivalents and restricted cash 21,790 18,500
Supplemental cash flow information:    
Cash paid for interest expense $ 784 $ 982