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Segment information (Tables) | 12 Months Ended
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Dec. 31, 2025
Segment Reporting [Abstract] |
Schedule of Significant Segment Expenses | The following table is a summary of the Company's significant segment expenses:
| Year ended December 31, 2025 |  | Year ended December 31, 2024
Direct research and development expenses: |  |  |
VTP-1000 Celiac | $ | 6,063 |  |  | $ | 5,486 |
Barinthus legacy assets 1 | 8,531 |  |  | 18,223 |
Total direct research and development expenses | $ | 14,594 |  |  | $ | 23,709 |
Indirect research and development expenses: |  |  |
Personnel-related (including share-based compensation) | 8,413 |  |  | 15,867 |
Facility related | 1,370 |  |  | 1,249 |
Other indirect costs | 1,187 |  |  | 1,411 |
Total indirect research and development expenses | 10,970 |  |  | 18,527 |
Total research and development expenses | $ | 25,564 |  |  | $ | 42,236 |
1 In January 2025, we announced a strategic focus on developing a pipeline in I&I, and the deprioritization of our programs in infectious disease and oncology. The following programs were previously presented separately and have been grouped collectively as "Barinthus Legacy Assets" for both years presented: VTP-300 HBV, VTP-850 Prostate Cancer, VTP-200 HPV, VTP-600 NSCLC, VTP-500 MERS and other and earlier stage programs.
Schedule of Long-Lived Assets | The following table summarizes the Company’s long-lived assets, which include the Company’s intangible assets, property and equipment, net and right-of-use assets by geography:
| Year ended December 31, 2025 |  | Year ended December 31, 2024
United States | $ | 19,449 |  |  | $ | 28,907 |
United Kingdom | — |  |  | 4,797 |
| $ | 19,449 |  |  | $ | 33,704 |

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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