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Segment information (Tables) | 6 Months Ended
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Jun. 30, 2026
Segment Reporting [Abstract] |
Schedule of Significant Segment Expenses | The following table is a summary of the Company's significant segment expenses:
|  |  |  |  | Three months ended June 30, 2026 |  | Three months ended June 30, 2025 |  | Change
Direct research and development expenses: |  |  |  |  |  |  |  |  |
VTP-1000 Celiac |  |  |  |  | $ | 2,936 |  |  | $ | 1,782 |  |  | $ | 1,154 |
Barinthus legacy assets 1 |  |  |  |  | 506 |  |  | 2,928 |  |  | (2,422) |
Total direct research and development expenses |  |  |  |  | 3,442 |  |  | 4,710 |  |  | (1,268) |
Indirect research and development expenses: |  |  |  |  |  |  |  |  |
Personnel-related (including share-based compensation) |  |  |  |  | 440 |  |  | 2,450 |  |  | (2,010) |
Facility related |  |  |  |  | 15 |  |  | 350 |  |  | (335) |
Other indirect costs |  |  |  |  | 26 |  |  | 443 |  |  | (417) |
Total indirect research and development expenses |  |  |  |  | 481 |  |  | 3,243 |  |  | (2,762) |
Total research and development expenses |  |  |  |  | $ | 3,923 |  |  | $ | 7,953 |  |  | $ | (4,030) |
|  |  |  |  | Six months ended June 30, 2026 |  | Six months ended June 30, 2025 |  | Change
Direct research and development expenses: |  |  |  |  |  |  |  |  |
VTP-1000 Celiac |  |  |  |  | $ | 4,358 |  |  | $ | 2,764 |  |  | $ | 1,594 |
Barinthus legacy assets 1 |  |  |  |  | 1,986 |  |  | 5,438 |  |  | (3,452) |
Total direct research and development expenses |  |  |  |  | 6,344 |  |  | 8,202 |  |  | (1,858) |
Indirect research and development expenses: |  |  |  |  |  |  |  |  |
Personnel-related (including share-based compensation) |  |  |  |  | 979 |  |  | 6,394 |  |  | (5,415) |
Facility related |  |  |  |  | 102 |  |  | 685 |  |  | (583) |
Other indirect costs |  |  |  |  | 91 |  |  | 962 |  |  | (871) |
Total indirect research and development expenses |  |  |  |  | 1,172 |  |  | 8,041 |  |  | (6,869) |
Total research and development expenses |  |  |  |  | $ | 7,516 |  |  | $ | 16,243 |  |  | $ | (8,727) |
1 In January 2025, we announced a strategic focus on developing a pipeline in I&I, and the deprioritization of our programs in infectious disease and oncology. The following programs were previously presented separately and have been grouped collectively as "Barinthus Legacy Assets" for both years presented: VTP-300 HBV, VTP-850 Prostate Cancer, VTP-200 HPV, VTP-600NSCLC, VTP-500 MERS and other and earlier stage programs.
Schedule of Long-Lived Assets | The following table summarizes the Company’s long-lived assets, which include the Company’s intangible assets, property and equipment, net, and right-of-use assets, by geography:
| June 30, 2026 |  | December 31, 2025
United States | $ | 17,701 |  |  | $ | 19,449 |
United Kingdom | — |  |  | — |
| $ | 17,701 |  |  | $ | 19,449 |

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