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Segment information (Tables)

6 Months Ended

Jun. 30, 2026

Segment Reporting [Abstract]

Schedule of Significant Segment Expenses

The following table is a summary of the Company's significant segment expenses:

															Three months ended June 30, 2026						Three months ended June 30, 2025						Change
Direct research and development expenses:
VTP-1000 Celiac															$	2,936					$	1,782					$	1,154
Barinthus legacy assets1															506						2,928						(2,422)
Total direct research and development expenses															3,442						4,710						(1,268)
Indirect research and development expenses:
Personnel-related (including share-based compensation)															440						2,450						(2,010)
Facility related															15						350						(335)
Other indirect costs															26						443						(417)
Total indirect research and development expenses															481						3,243						(2,762)
Total research and development expenses															$	3,923					$	7,953					$	(4,030)

															Six months ended June 30, 2026						Six months ended June 30, 2025						Change
Direct research and development expenses:
VTP-1000 Celiac															$	4,358					$	2,764					$	1,594
Barinthus legacy assets1															1,986						5,438						(3,452)
Total direct research and development expenses															6,344						8,202						(1,858)
Indirect research and development expenses:
Personnel-related (including share-based compensation)															979						6,394						(5,415)
Facility related															102						685						(583)
Other indirect costs															91						962						(871)
Total indirect research and development expenses															1,172						8,041						(6,869)
Total research and development expenses															$	7,516					$	16,243					$	(8,727)

1 In January 2025, we announced a strategic focus on developing a pipeline in I&I, and the deprioritization of our programs in infectious disease and oncology. The following programs were previously presented separately and have been grouped collectively as "Barinthus Legacy Assets" for both years presented: VTP-300 HBV, VTP-850 Prostate Cancer, VTP-200 HPV, VTP-600NSCLC, VTP-500 MERS and other and earlier stage programs.

Schedule of Long-Lived Assets

The following table summarizes the Company’s long-lived assets, which include the Company’s intangible assets, property and equipment, net, and right-of-use assets, by geography:

			June 30, 2026						December 31, 2025
United States			$	17,701					$	19,449
United Kingdom			—						—
			$	17,701					$	19,449

X

- Definition

Tabular disclosure of long-lived asset located in country of domicile and foreign country in which asset is held if it is not provided as part of reportable segment information. Long-lived asset excludes financial instrument, long-term customer relationship of financial institution, mortgage and other servicing rights, deferred policy acquisition cost, and deferred tax asset. Includes, but is not limited to, subtotal of geographical information about group of countries.

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