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Commitments and Contingencies - Additional Information (Details) $ in Thousands			3 Months Ended		6 Months Ended
	Jun. 14, 2022 ft²	Sep. 03, 2021 USD ($) ft²	Jun. 30, 2026 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2026 USD ($)	Jun. 30, 2025 USD ($)	Dec. 31, 2025 USD ($)
Other Commitments [Line Items]
Right-of-use asset			$ 1,618		$ 1,618		$ 1,638
Transaction-related legal and advisory fees			1,500	$ 0	2,400	$ 0
Oxfordshire
Other Commitments [Line Items]
Size of space under lease agreement (in square feet) | ft²		31,000
Refundable security deposit		$ 700
Right-of-use asset			$ 0		$ 0
Maryland
Other Commitments [Line Items]
Size of space under lease agreement (in square feet) | ft²	19,700
Minimum | In-License Agreements
Other Commitments [Line Items]
Percentage of future royalties for direct sales of a covered product					1.00%
Net payments received for allowable sublicenses of technology developed					1.00%
Maximum | In-License Agreements
Other Commitments [Line Items]
Percentage of future royalties for direct sales of a covered product					5.00%
Net payments received for allowable sublicenses of technology developed					5.00%

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- Definition

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- Definition

Amount of expense for acquisition-related cost incurred to effect business combination. Includes, but is not limited to, finder's fee; advisory, legal, accounting, valuation, and other professional and consulting fees; and general administrative cost, including cost of maintaining internal acquisition department.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 805
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 7
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479328/805-10-50-7

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 805
-SubTopic 10
-Name Accounting Standards Codification
-Section 25
-Paragraph 23
-Publisher FASB
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- Definition

Amount of lessee's right to use underlying asset under operating lease.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 45
-Paragraph 1
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479041/842-20-45-1

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The amount of an asset, typically cash, provided to a counterparty to provide certain assurance of performance by the entity pursuant to the terms of a written or oral agreement, such as a lease.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(17))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S50
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-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480657/210-10-S50-7

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