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Collaboration and License Agreements - Additional Information (Details) - USD ($) |  |  | 6 Months Ended |  |
--- | --- | --- | --- | --- | ---
Sep. 10, 2018 | Feb. 24, 2016 | Jun. 30, 2019 | Jun. 30, 2018 | Jan. 01, 2019 | Dec. 31, 2018
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Deferred revenue |  |  | $ 7,129,000 |  | $ 8,029,000 | $ 8,436,000
Development and Commercial License Agreement | Servier |  |  |  |  |  |
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Upfront payment |  | $ 105,000,000 |  |  |  |
Recognized revenue under agreement |  |  | 3,000,000 | $ 2,900,000 |  |
Deferred revenue |  |  | 85,200,000 |  |  | 88,600,000
Development or sales-based milestone payments |  |  | 0 | $ 0 |  |
Development and Commercial License Agreement | Servier | Current Liabilities |  |  |  |  |  |
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Deferred revenue |  |  | 5,900,000 |  |  | 6,400,000
Development and Commercial License Agreement | Servier | Maximum |  |  |  |  |  |
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Total payments to be received |  | 1,600,000,000 |  |  |  |
Aggregate milestone payments |  | 1,500,000,000 |  |  |  |
Development milestone payments |  | 401,300,000 |  |  |  |
Commercial milestone payments |  | $ 1,100,000,000 |  |  |  |
Collaboration and License Agreement | Gilead |  |  |  |  |  |
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Recognized revenue under agreement |  |  | 6,700,000 |  |  |
Deferred revenue |  |  | 1,200,000 |  |  | 2,300,000
Development or sales-based milestone payments |  |  | $ 0 |  |  |
Research funding payment term | 3 years |  | 3 years |  |  |
Semi-annual research funding payments | $ 40,000,000 |  |  |  |  |
Collaboration and License Agreement | Gilead | Current Liabilities |  |  |  |  |  |
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Deferred revenue |  |  | $ 1,200,000 |  |  | $ 2,300,000
Collaboration and License Agreement | Gilead | Maximum |  |  |  |  |  |
Collaboration and License Agreements [Line items] |  |  |  |  |  |
Development milestone payments | 105,000,000 |  |  |  |  |
Commercial milestone payments | 340,000,000 |  |  |  |  |
Receivable from research funding | 40,000,000 |  |  |  |  |
Development and commercial milestone payments | $ 445,000,000 |  |  |  |  |

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- Definition Aggregate payment on collaboration agreement to be received. + References No definition available. + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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