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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2022 | Sep. 30, 2021
Cash flows from operating activities: |  |
Net loss | $ (83,149) | $ (8,312)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 5,838 | 6,806
Share-based compensation | 14,661 | 12,079
Loss on disposal of assets | 58 | 23
Non-cash interest expense | 210 | 42
Amortization of right-of-use assets | 891 | 897
Non-cash consideration received from collaboration partners |  | (17,894)
Change in fair value of equity investments |  | (274)
Loss from equity method investment | 4,183 |
Amortization of discount on note receivable | (264) |
Changes in operating assets and liabilities: |  |
Prepaid expenses | 5,142 | (323)
Accounts receivable | (227) | 9,512
Other assets and other current assets | (4,689) | 47
Accounts payable | (187) | 240
Other liabilities and other current liabilities | (2,237) | (976)
Deferred revenue | 37,209 | 2,391
Lease liabilities and right-of-use assets | (1,349) | (1,430)
Contract liabilities |  | 10,000
Net cash (used in) provided by operating activities | (23,910) | 12,828
Cash flows from investing activities: |  |
Purchases of property, equipment and software | (2,687) | (3,548)
Purchases of intangible assets |  | (750)
Net cash used in investing activities | (2,687) | (4,298)
Cash flows from financing activities: |  |
Proceeds from stock option exercises | 387 | 5,757
Proceeds from employee stock purchase plan | 443 | 804
Proceeds from offering of common stock, net of issuance costs | 49,345 | 18,130
Proceeds from issuance of common stock to collaboration partners | 25,000 | 35,000
Borrowings from revolving credit facility, net of issuance costs | 19,810 |
Proceeds from issuance of term loan, net of issuance costs paid to lender |  | 2,465
Payments of debt issuance costs |  | (13)
Net cash provided by financing activities | 94,985 | 62,143
Net increase in cash and cash equivalents | 68,388 | 70,673
Cash and cash equivalents—beginning of period | 143,663 | 89,798
Cash and cash equivalents —end of period | 212,051 | 160,471
Supplemental disclosures of noncash activities: |  |
Property, equipment and software additions included in accounts payable and accrued expenses other current liabilities | 232 | 695
Cash paid for interest | $ 422 | 36
Unsettled at-the-market issuances of common stock included in other current assets |  | 549
Contract liability accrual related to Servier Program Purchase Agreement milestones |  | 10,000
Non-cash consideration received from collaboration partners |  | $ 17,894

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