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Income Taxes - Additional Information (Details) - USD ($) |  | 12 Months Ended
--- | --- | ---
Jan. 01, 2025 | Dec. 31, 2030 | Dec. 31, 2029 | Dec. 31, 2028 | Dec. 31, 2027 | Dec. 31, 2026 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Increase (decrease) in valuation allowance of net deferred tax assets |  |  |  |  |  |  | $ (2,300,000) |  |
Net Operating loss carry forwards expiration year |  |  |  |  |  |  | 2027 |  |
Ownership percentage change in outstanding common stock period |  |  |  |  |  |  | 3 years |  |
Ownership Percentage Change Of Outstanding Common Stock |  |  |  |  |  |  | 50.00% |  |
Uncertain tax position |  |  |  |  |  |  | $ 0 |  |
Unrecognized tax benefits |  |  |  |  |  |  | 0 | $ 0 |
Unrecognized tax benefits, income tax penalties and interest accrued |  |  |  |  |  |  | $ 0 | 0 |
Percentage of decrease in corporate income tax rate |  |  |  |  |  |  | 2.50% |  |
GILTI tax expense |  |  |  |  |  |  | $ 0 | 0 |
2021 Appropriations Act |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Increase (decrease) in valuation allowance of net deferred tax assets |  |  |  |  |  |  | (8,500,000) |  |
Forecast |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Percentage of decrease in corporate income tax rate | 2.25% | 0.00% | 1.00% | 1.00% | 2.00% | 2.00% |  |  |
Federal |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Net operating loss carryforwards |  |  |  |  |  |  | 235,500,000 | 195,000,000 |
Federal contribution carryforwards |  |  |  |  |  |  | $ 100,000 | $ 200,000 |
Federal contribution expiration beginning year |  |  |  |  |  |  | 2026 | 2026 |
Federal | Research and Development |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Tax credit carryforwards |  |  |  |  |  |  | $ 20,200,000 | $ 17,200,000 |
Tax credit carry forwards expiration beginning year |  |  |  |  |  |  | 2029 |  |
Federal | Orphan Drug Tax Credit Carry forward |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Tax credit carryforwards |  |  |  |  |  |  | $ 13,500,000 |  |
Tax credit carry forwards expiration beginning year |  |  |  |  |  |  | 2038 |  | 2038
State |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Net operating loss carryforwards |  |  |  |  |  |  | $ 212,000,000 | 166,800,000 |
State | Research and Development |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Tax credit carry forwards expiration beginning year |  |  |  |  |  |  | 2030 |  |
Maximum [Member] | State | Research and Development |  |  |  |  |  |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Tax credit carryforwards |  |  |  |  |  |  | $ 100,000 | $ 100,000 |

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