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Description of Business and Summary of Significant Accounting Policies - Additional Information (Details) |  | 12 Months Ended |
--- | --- | --- | ---
Feb. 13, 2024 | Dec. 31, 2024 USD ($) shares | Dec. 31, 2023 USD ($) | Aug. 15, 2023 USD ($)
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Stock split, conversion ratio | 30 |  |  |
Net income (loss) |  | $ (7,167,000) | $ 61,319,000 |
Retained earnings accumulated deficit |  | 482,464,000 | 489,631,000 |
Investments under equity method carrying amount |  | 0 |  |
Revenue recorded included in deferred revenue |  | $ 59,100,000 |  |
Tax benefits recognized,likelihood upon ultimate settlement |  | The tax benefits recognized in the financial statements from such a position is measured based on the largest benefit that has a greater than 50% likelihood of being realized upon ultimate settlement. |  |
Restricted cash |  | $ 22,569,000 | $ 0 |
Warrants outstanding | shares |  | 2,500,000 |  |
March 2024 Public Offering |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Warrants outstanding | shares |  | 2,500,000 |  |
Elo | Promissory Note |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Notes received |  | $ 10,000,000 |  |
Minimum | Investments under Equity Method |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Voting interests of the investee |  | 20.00% |  |
Novartis |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Revenue |  |  | 38.00% |
TG Therapeutics |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Revenue |  | 12.00% |  |
Prevail |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Revenue |  | 77.00% | 62.00% |
Imugene |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Aggregate principal amount |  |  |  | $ 13,000,000
iECURE |  |  |  |
Description Of Business And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Investment in equity securities |  | $ 3,200,000 | $ 3,200,000 |

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- Definition Ratio applied to the conversion of stock split, for example but not limited to, one share converted to two or two shares converted to one. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 4 -Subparagraph (SAB Topic 4.C) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480008/505-10-S99-4 + Details
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