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Segment Reporting - Summary of Significant Research and Development and General and Administrative Expense to CODM (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023
Revenue | $ 68,696 | $ 48,727
Platform development and early-stage research expenses [Abstract] |  |
Share based compensation | 12,604 | 14,040
Depreciation and amortization | 3,404 | 6,817
Total research and development expenses | 59,559 | 53,375
General and administrative expense |  |
Total general and administrative expenses | 35,299 | 39,088
Total operating expenses | 94,858 | 92,463
Operating loss | (26,162) | (43,736)
Total other income | 33,329 | 1,209
Income (loss) from continuing operations | 7,167 | (42,527)
Loss from discontinued operations | 0 | (18,792)
Net income (loss) | 7,167 | (61,319)
Operating Segments |  |
Revenue | 68,696 | 48,727
Platform development and early-stage research expenses [Abstract] |  |
Employee-related costs (other than share based compensation) | 18,753 | 19,788
Share based compensation | 2,560 | 3,642
Laboratory supplies and services | 3,016 | 5,741
CMOs and outsourced research and development | 1,083 | 4,753
Facility-related costs, laboratory equipment, and maintenance | 3,082 | 3,308
Depreciation and amortization | 2,718 | 4,022
Licensing fees and other research and development costs | 2,428 | 2,508
Total research and development expenses | 59,559 | 53,375
General and administrative expense |  |
Employee-related costs (including share-based compensation) | 21,861 | 22,517
Consulting and professional services | 6,327 | 7,445
Other operating expenses and all other costs | 7,111 | 9,126
Total general and administrative expenses | 35,299 | 39,088
Total operating expenses | 94,858 | 92,463
Operating loss | (26,162) | (43,736)
Total other income | 33,329 | 1,209
Income (loss) from continuing operations | 7,167 | (42,527)
Loss from discontinued operations |  | (18,792)
Net income (loss) | 7,167 | (61,319)
Operating Segments | PBGENE-HBV |  |
Direct research and development expenses by product candidate: |  |
External development costs | 16,111 | 9,261
Operating Segments | PBGENE-3243 |  |
Direct research and development expenses by product candidate: |  |
External development costs | $ 9,808 | $ 352

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