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Segment Reporting (Tables)

12 Months Ended

Dec. 31, 2024

Segment Reporting [Abstract]

Summary of Significant Research and Development and General and Administrative Expense to CODM

The table below summarizes the significant research and development and general and administrative expense categories regularly provided to the CODM:

		Years Ended December 31,
(in thousands)		2024				2023
Revenue		$	68,696			$	48,727
Operating expenses
Research and development
Direct research and development expenses by product candidate:
PBGENE-HBV external development costs			16,111				9,261
PBGENE-3243 external development costs			9,808				352
Platform development and early-stage research expenses:
Employee-related costs (other than share-based compensation)			18,753				19,788
Share-based compensation			2,560				3,642
Laboratory supplies and services			3,016				5,741
CMOs and outsourced research and development			1,083				4,753
Facility-related costs, laboratory equipment, and maintenance			3,082				3,308
Depreciation and amortization			2,718				4,022
Licensing fees and other research and development costs			2,428				2,508
Total research and development expenses		$	59,559			$	53,375
General and administrative expense
Employee-related costs (including share-based compensation)			21,861				22,517
Consulting and professional services			6,327				7,445
Other operating expenses and all other costs			7,111				9,126
Total general and administrative expenses		$	35,299			$	39,088
Total operating expenses		$	94,858			$	92,463
Operating loss			(26,162	)			(43,736	)
Total other income (expense)			33,329				1,209
Income (loss) from continuing operations		$	7,167			$	(42,527	)
Loss from discontinued operations			—				(18,792	)
Net income (loss)		$	7,167			$	(61,319	)

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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- References

No definition available.

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