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Collaboration and License Agreements - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 06, 2025
Jan. 07, 2024
Aug. 15, 2023
Jun. 14, 2022
Jul. 31, 2022
Dec. 31, 2024
Dec. 31, 2023
Collaboration and License Agreements [Line items]              
Common stock, shares issued           8,229,730 4,191,053
Revenue           $ 68,696,000 $ 48,727,000
Deferred revenue           2,957,000 12,035,000
Research and development           59,559,000 53,375,000
Prepaid expenses           6,441,000 5,977,000
Revenue recorded included in deferred revenue           59,100,000  
Imugene              
Collaboration and License Agreements [Line items]              
Milestone payments to be received for additional targets     $ 206,000,000        
Revenue           0  
Cash received from sale of business     8,000,000     9,750,000  
Aggregate principal amount     13,000,000        
Imugene | Maximum              
Collaboration and License Agreements [Line items]              
Milestone payments to be received for additional targets     $ 145,000,000        
Research and Development Arrangement              
Collaboration and License Agreements [Line items]              
Additional cash payment   $ 2,250,000          
Percentage of premium over the volume-weighted-average-price of the company’s common stock   100.00%          
Initial milestone payment   $ 7,500,000          
Cash milestone payment   5,250,000          
Research and Development Arrangement | Current Liabilities              
Collaboration and License Agreements [Line items]              
Deferred revenue           3,000,000 7,400,000
Research and Development Arrangement | Novartis Pharma AG              
Collaboration and License Agreements [Line items]              
Milestone payments to be received for additional targets       $ 1,400,000,000      
Revenue           6,400,000 22,700,000
Deferred revenue related to agreement           26,300,000 32,400,000
Research and Development Arrangement | Novartis Pharma AG | Stock Purchase Agreement              
Collaboration and License Agreements [Line items]              
Upfront cash payment         $ 50,000,000    
Sale of stock, number of shares issued in transaction       413,581      
Aggregate purchase price       $ 25,000,000      
Sale of stock, price per share       $ 60.3      
Percentage of premium over the volume-weighted-average-price of the company’s common stock       20.00%      
Research and Development Arrangement | TG License              
Collaboration and License Agreements [Line items]              
Upfront cash payment   10,000,000          
Additional cash payment   7,500,000          
Additional cash payment   $ 5,250,000          
First additional cash payment date   Feb. 05, 2024          
Additional cash payment   $ 2,250,000          
Second additional cash payment date   Feb. 05, 2024          
Sale of stock, number of shares issued in transaction   97,360          
Percentage of premium over the volume-weighted-average-price of the company’s common stock   100.00%          
Shares issued price per share   $ 11.166          
Milestone payments to be received for additional targets   $ 3,000,000          
Cash payable in exchange for the issuance of stock   $ 10,000,000          
Percentage of value of each additional milestone payment   50.00%          
Equity upon the issuance of the shares   $ 3,000,000          
Research and Development Arrangement | TG License | Subsequent Event              
Collaboration and License Agreements [Line items]              
Third additional cash payment date Jan. 06, 2025            
Sale of stock, number of shares issued in transaction 220,712            
Deferred cash payments $ 2,500,000            
Research and Development Arrangement | TG License | Maximum              
Collaboration and License Agreements [Line items]              
Milestone payments to be received for additional targets   $ 288,600,000          
Research and Development Arrangement | Prevail              
Collaboration and License Agreements [Line items]              
Revenue           52,700,000 26,000,000
Deferred revenue related to agreement           0 52,700,000
Research and Development Arrangement | Prevail | Current Liabilities              
Collaboration and License Agreements [Line items]              
Deferred revenue             4,700,000
Research and Development Arrangement | iECURE              
Collaboration and License Agreements [Line items]              
Carrying value of fair value           $ 0 $ 600,000