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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate and Income Tax Benefit (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Reconciliation of income taxes amount, Amount    
Income tax expense at statutory rate, Amount $ 1,501 $ (12,877)
State income taxes, net of federal tax benefit, Amount 46 (1,774)
Non-deductible expenses, Amount 97 81
Stock compensation - nondeductible, Amount 1,032 681
Stock compensation - forfeitures, Amount 1,136 3,176
Change in fair value, Amount (6,507) 4
Change in state impact on IRC section 174, Amount (553)  
R&D and orphan drug credits, Amount (2,944) (6,078)
Other, Amount (11) 657
Change in state tax rate 8,464 (1,632)
Change in valuation allowance, Amount $ (2,261) $ 17,762
Reconciliation of income taxes rate, Percentage    
Income tax expense at statutory rate, Percentage 21.00% 21.00%
State income taxes, net of federal tax benefit, Percentage 0.60% 2.90%
Non-deductible expenses, Percentage 1.40% 0.00%
Stock compensation - nondeductible, Percentage 14.40% (1.20%)
Stock compensation - forfeitures, Percentage 15.90% (5.20%)
Change in fair value, Percent (91.10%) 0.00%
Change in state impact on IRC section 174, Percent (7.70%)  
R&D and orphan drug credits, Percentage (41.20%) 9.90%
Other, Percentage (0.10%) (1.10%)
Change in state tax rate 118.40% 2.70%
Change in valuation allowance, Percentage (31.60%) (29.00%)
Total effective tax rate 0.00% 0.00%