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CONDENSED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Treasury Stock
Beginning balance (in shares) at Dec. 31, 2023   4,191,053      
Beginning balance at Dec. 31, 2023 $ 18,861 $ 1 $ 509,443 $ (489,631) $ (952)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   9,037      
Issuance of common stock under employee stock purchase plan 112   112    
Share-based compensation expense 2,906   2,906    
Proceeds from issuance of common stock to collaboration partners and licensees (in shares)   97,360      
Proceeds from issuance of common stock to collaboration partners and licensees 905   905    
Proceeds from issuance of common stock and warrants through underwritten offering, net of issuance cost (in shares)   2,500,000      
Proceeds from issuance of common stock and warrants through underwritten offering, net of issuance cost 4,610   4,610    
Proceeds from issuance of common stock through ATM facility, net of issuance cost (in shares)   98,943      
Proceeds from issuance of common stock through ATM facility, net of issuance cost 1,224   1,224    
Restricted stock units vested (in shares)   46,861      
Net income (loss) 8,588     8,588  
Ending balance (in shares) at Mar. 31, 2024   6,943,254      
Ending balance at Mar. 31, 2024 37,206 $ 1 519,200 (481,043) (952)
Beginning balance (in shares) at Dec. 31, 2023   4,191,053      
Beginning balance at Dec. 31, 2023 18,861 $ 1 509,443 (489,631) (952)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net income (loss) 41,337        
Ending balance (in shares) at Jun. 30, 2024   7,150,385      
Ending balance at Jun. 30, 2024 74,714 $ 1 523,959 (448,294) (952)
Beginning balance (in shares) at Mar. 31, 2024   6,943,254      
Beginning balance at Mar. 31, 2024 37,206 $ 1 519,200 (481,043) (952)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Share-based compensation expense 2,928   2,928    
Proceeds from issuance of common stock through ATM facility, net of issuance cost (in shares)   144,735      
Proceeds from issuance of common stock through ATM facility, net of issuance cost 1,531   1,531    
Restricted stock units vested (in shares)   37,396      
Net income (loss) 32,749     32,749  
Proceeds from issuance of common stock, net of issuance cost (in shares)   25,000      
Proceeds from issuance of common stock, net of issuance cost 300   300    
Ending balance (in shares) at Jun. 30, 2024   7,150,385      
Ending balance at Jun. 30, 2024 $ 74,714 $ 1 523,959 (448,294) (952)
Beginning balance (in shares) at Dec. 31, 2024 8,229,730 8,229,730      
Beginning balance at Dec. 31, 2024 $ 56,393 $ 1 539,808 (482,464) (952)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   30,999      
Issuance of common stock under employee stock purchase plan 140   140    
Share-based compensation expense 2,822   2,822    
Proceeds from issuance of common stock through ATM facility, net of issuance cost (in shares)   1,818,886      
Proceeds from issuance of common stock through ATM facility, net of issuance cost 9,516   9,516    
Restricted stock units vested (in shares)   275,540      
Net income (loss) (20,565)     (20,565)  
Proceeds from issuance of common stock to licensees (in shares)   220,712      
Proceeds from issuance of common stock to licensees 1,031   1,031    
Ending balance (in shares) at Mar. 31, 2025   10,575,867      
Ending balance at Mar. 31, 2025 $ 49,337 $ 1 553,317 (503,029) (952)
Beginning balance (in shares) at Dec. 31, 2024 8,229,730 8,229,730      
Beginning balance at Dec. 31, 2024 $ 56,393 $ 1 539,808 (482,464) (952)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net income (loss) $ (44,085)        
Ending balance (in shares) at Jun. 30, 2025 11,663,996 11,663,996      
Ending balance at Jun. 30, 2025 $ 34,054 $ 1 561,554 (526,549) (952)
Beginning balance (in shares) at Mar. 31, 2025   10,575,867      
Beginning balance at Mar. 31, 2025 49,337 $ 1 553,317 (503,029) (952)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Share-based compensation expense 2,937   2,937    
Proceeds from issuance of common stock through ATM facility, net of issuance cost (in shares)   1,036,488      
Proceeds from issuance of common stock through ATM facility, net of issuance cost 5,300   5,300    
Restricted stock units vested (in shares)   51,641      
Net income (loss) $ (23,520)     (23,520)  
Ending balance (in shares) at Jun. 30, 2025 11,663,996 11,663,996      
Ending balance at Jun. 30, 2025 $ 34,054 $ 1 $ 561,554 $ (526,549) $ (952)