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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Cash flows from operating activities:    
Net loss $ (21,498) $ (17,227)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 19 18
Amortization of warrant issuance costs 61 0
Stock-based compensation 5,326 5,952
Change in value of derivative liability 117 (2,126)
Changes in assets and liabilities:    
Prepaid expenses and other assets 182 (3,642)
Income tax liability (8) 0
Accounts payable and accrued liabilities (2,176) 681
Related-party payable (81) 0
Royalty payable (5,071) 0
Deferred revenue 1,375 1,708
Net cash used in operating activities (21,754) (14,636)
Cash flows from investing activities:    
Purchase of property and equipment (4) (17)
Purchase of investments (6,234) (11,928)
Proceeds from sale or maturity of investments 18,009 15,829
Net cash provided by investing activities 11,771 3,884
Cash flows from financing activities:    
Proceeds from exercise of options 165 68
Proceeds from exercise of warrants 431 9
Proceeds from sale of common stock 719 0
Net cash provided by financing activities 1,315 77
Net decrease in cash and cash equivalents (8,668) (10,675)
Cash and cash equivalents, beginning of period 18,658 19,173
Cash and cash equivalents, end of period 9,990 8,498
Non-cash transactions    
Fair value of warrants issued for services $ 121 $ 0