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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash flows from operating activities:    
Net loss $ (8,610) $ (5,855)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 6 7
Stock-based compensation 1,234 1,692
Amortization of warrant issuance costs (30) 0
Change in value of derivative liability 0 117
Changes in assets and liabilities:    
Prepaid expenses (108) (208)
Accounts payable and accrued liabilities 1,643 (2,248)
Payroll accrual (1,383) 0
Income tax liability 0 (13)
Related party payable (11) (81)
Deferred revenue (375) (375)
Net cash used in operating activities (7,634) (6,964)
Cash flows from investing activities:    
Purchase of property and equipment (2) (4)
Purchase of investments (2,752) (2,932)
Proceeds from sale or maturity of investments 4,116 4,101
Net cash provided by investing activities 1,362 1,165
Cash flows from financing activities:    
Proceeds from exercise of options 20 0
Proceeds from exercise of warrants 0 431
Proceeds from sale of common stock 6,795 0
Net cash provided by financing activities 6,815 431
Net increase (decrease) in cash and cash equivalents 543 (5,368)
Cash and cash equivalents, beginning of period 8,726 18,658
Cash and cash equivalents, end of period $ 9,269 $ 13,290