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v3.25.2

Related parties (Details Narrative) |  |  |  |  |  |  |  | 6 Months Ended |  |  |  |  |  |
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Jul. 01, 2025 EUR (€) | May 31, 2025 EUR (€) | May 12, 2025 EUR (€) | Apr. 01, 2025 EUR (€) | Feb. 29, 2024 EUR (€) | Apr. 20, 2023 EUR (€) | Jul. 01, 2022 EUR (€) | Jun. 30, 2025 USD ($) | Jun. 30, 2025 EUR (€) shares | Jun. 30, 2024 EUR (€) shares | Mar. 31, 2025 shares | Dec. 31, 2024 EUR (€) shares | Jul. 31, 2024 shares | Mar. 31, 2024 shares | Dec. 31, 2023 EUR (€) | Jun. 30, 2023 EUR (€) shares
Other general and administrative costs |  |  |  |  |  |  |  |  | € 51,000 |  |  |  |  |  |  |
Depreciation expenses |  |  |  |  |  |  |  |  | 14,000 |  |  |  |  |  |  |
Insurance cost limited liability |  |  |  |  |  |  |  |  | 93,000 |  |  |  |  |  |  |
Membership fees |  |  |  |  |  |  |  |  | 30,000 |  |  |  |  |  |  |
Patent maintenance |  |  |  |  |  |  |  |  | 12,000 |  |  |  |  |  |  |
Other various minor expenses |  |  |  |  |  |  |  |  | 131,000 |  |  |  |  |  |  |
Billed paid |  |  |  |  |  |  |  |  | 5,000 | € 5,000 |  |  |  |  |  |
Compensation expense |  |  |  |  |  |  |  |  | € 352,364 | 232,768 |  |  |  |  |  |
Vested shares | shares |  |  |  |  |  |  |  |  | 803,524 |  |  | 456,098 |  |  |  |
Paid in cash |  |  |  |  |  |  |  |  | € 3,982 |  |  | € 4,000 |  |  |  |
Accrued expenses to related parties |  |  |  |  |  |  |  |  | 230,712 |  |  | 1,031,345 |  |  |  |
Amended and Restated OSR License Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront fee |  |  |  |  |  |  |  |  | € 250,000 |  |  |  |  |  |  |
Other Commitments, Description |  |  |  |  |  |  |  | The Company is also obligated to carry out its development activities using qualified and experienced professionals and a sufficient level of resources. In particular, consistent with the terms of the Original OSR License Agreement, the ARLA continues to require the Company to invest (a) at least €5,425,000 with respect to the development of the licensed products, and (b) at least €2,420,000 with respect to the manufacturing of such licensed products (subject to certain adjustments). | The Company is also obligated to carry out its development activities using qualified and experienced professionals and a sufficient level of resources. In particular, consistent with the terms of the Original OSR License Agreement, the ARLA continues to require the Company to invest (a) at least €5,425,000 with respect to the development of the licensed products, and (b) at least €2,420,000 with respect to the manufacturing of such licensed products (subject to certain adjustments). |  |  |  |  |  |  |
Sublicense Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Taxes and licenses |  |  |  |  |  | € 875,000 |  |  |  |  |  |  |  |  |  |
Amendment to OSR Amendedand Restated License Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash consideration |  |  |  |  |  |  |  |  | € 200,000 |  |  |  |  |  |  |
Amendment to OSR Amendedand Restated License Agreement [Member] | First Solid Cancer Indication Option Fee [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating costs and expenses |  |  |  |  |  |  |  |  | 11,800,000 |  |  |  |  |  |  |
Amendment to OSR Amendedand Restated License Agreement [Member] | Second Solid Cancer Indication Option Fee [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Option fee |  |  |  |  |  |  |  |  | 1,000,000.0 |  |  |  |  |  |  |
Amended and Restated License Agreement [Member] | Second Solid Cancer Indication Option Fee [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Option fee |  |  |  |  |  |  |  |  | 400,000 |  |  |  |  |  |  |
First Indication [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Future option fees |  |  |  |  |  |  |  |  | 1,000,000.0 |  |  |  |  |  |  |
Second Indication [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Future option fees |  |  |  |  |  |  |  |  | 500,000 |  |  |  |  |  |  |
Third Indication [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Future option fees |  |  |  |  |  |  |  |  | 300,000 |  |  |  |  |  |  |
American Depository Shares [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares received | shares |  |  |  |  |  |  |  |  |  |  | 856,602 |  |  | 72,908 |  |
Pierluigi Paracchi [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross amount |  |  |  |  |  |  |  |  | € 0 | 168,000 |  |  |  |  |  | € 168,000
Gross amount |  |  |  |  |  |  |  |  |  | 336,000 |  |  |  |  |  |
Non qualified shares received | shares |  |  |  |  |  |  |  |  | 80,000 |  |  |  |  |  |  |
Social contribution amount |  |  |  |  |  |  |  |  | € 307,000 | 300,000 |  |  |  |  |  |
Pierluigi Paracchi [Member] | Trattamento Di Fine Rapporto [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Social contribution amount |  |  |  |  |  |  |  |  | € 364,000 | 357,000 |  |  |  |  |  |
Pierluigi Paracchi [Member] | American Depository Shares [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares received | shares |  |  |  |  |  |  |  |  | 120,000 |  |  |  |  |  |  |
Dr Carlo Russos LLC [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross amount |  |  |  |  |  |  |  |  | € 0 |  |  | € 260,000 |  |  | € 260,000 |
Non qualified shares received | shares |  |  |  |  |  |  |  |  | 65,000 |  |  |  |  |  |  |
Compensation expense |  |  |  |  |  |  |  |  | € 226,379 | 226,379 |  |  |  |  |  |
Dr Carlo Russos LLC [Member] | American Depository Shares [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares received | shares |  |  |  |  |  |  |  |  |  |  |  |  | 100,000 |  |  |
Richard Slansky [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Compensation expense |  |  |  |  |  |  |  |  | 399,673 | 399,673 |  |  |  |  |  |
Related Party [Member] | OSR Sponsor Research Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments to acquire |  |  |  |  |  |  |  |  | 500,000 |  |  |  |  |  |  |
Studio Legale Lexia [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Accrued expenses to related parties |  |  |  |  |  |  |  |  | 10,070 |  |  |  |  |  |  |
Pierluigi Paracchi [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross salary |  |  |  | € 451,560 |  |  |  |  |  |  |  |  |  |  |  |
Percentage of annual bonus |  |  |  | 40.00% |  |  |  |  |  |  |  |  |  |  |  |
Director [Member] | Pierluigi Paracchi [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issued invoices |  | € 45,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Naldini [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issued invoices |  |  |  |  |  |  |  |  | 50,000 | 50,000 |  |  |  |  |  |
Annual fee |  |  | € 50,000 |  |  |  | € 100,000 |  |  |  |  |  |  |  |  |
Dr.Gentner [[Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issued invoices |  |  |  |  |  |  |  |  | € 22,500 | 22,500 |  |  |  |  |  |
Annual fee |  |  |  |  |  |  | € 22,500 |  |  |  |  |  |  |  |  |
One time fee payment |  |  |  |  | € 15,000 |  |  |  |  |  |  |  |  |  |  |
Dr.Gentner [[Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Agreement term description | The agreement will remain in effect for a fixed term of one (1) year, from July 1, 2025, through June 30, 2026. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Dr.Gentner [[Member] | Maximum [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Annual compensation | € 45,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Dr.Gentner [[Member] | Minimum [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Annual compensation | € 22,500 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Dr Carlo Russos LLC [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of annual bonus |  |  |  |  |  |  |  | 30.00% | 30.00% |  |  |  |  |  |  |
Gross amount |  |  |  |  |  |  |  |  | € 329,000 | € 329,000 |  |  |  |  |  |
Annual gross salary | $ |  |  |  |  |  |  |  | $ 500,000 |  |  |  |  |  |  |  |
Richard Slansky [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of annual bonus |  |  |  |  |  |  |  | 30.00% | 30.00% | 50.00% |  |  |  |  |  |
Gross amount |  |  |  |  |  |  |  |  | € 98,832 |  |  |  |  |  |  | € 49,416
Gross amount |  |  |  |  |  |  |  |  | 243,000 | € 243,000 |  |  |  |  |  |
Annual compensation | $ |  |  |  |  |  |  |  | $ 375,000 |  |  |  |  |  |  |  |
Vested shares | shares |  |  |  |  |  |  |  |  |  | 7,669 |  |  |  |  |  | 15,338
Vested amount |  |  |  |  |  |  |  |  |  | € 23,998 |  |  |  |  |  | € 47,997
Paid in cash |  |  |  |  |  |  |  |  |  | 18,531 |  |  |  |  |  | 45,902
Bonus amount accrued |  |  |  |  |  |  |  |  |  | 108,000 |  |  |  |  |  |
Accrued performance bonuses |  |  |  |  |  |  |  |  | € 0 |  |  |  |  |  |  |
Richard Slansky [Member] | Finance Employee One [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Paid in cash |  |  |  |  |  |  |  |  |  | 3,089 |  |  |  |  |  | 2,196
Richard Slansky [Member] | Finance Employee Two [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Paid in cash |  |  |  |  |  |  |  |  |  | 1,853 |  |  |  |  |  | € 1,318
Richard Slansky [Member] | Finance Employee Three [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Paid in cash |  |  |  |  |  |  |  |  |  | € 1,235 |  |  |  |  |  |

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