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Pay vs Performance Disclosure - USD ($)
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Pay vs Performance Disclosure      
Pay vs Performance Disclosure, Table
Year   Summary
Compensation
Table Total for
PEO($)(1)		     Compensation
Actually Paid
to PEO($)(2)		     Average
Summary
Compensation
Table Total
for Non-PEO
Named
Executive
Officers($)		     Average
Compensation
Actually Paid
to Non-PEO
Named
Executive
Officers($)(3)		     Value of
Initial Fixed
$100
Investment
Based On
Total
Shareholder
Return($)		     Net Income/(Loss)
($)		  
2024   $ 899,695     $ 953,144     $ 895,556     $ 770,636     $ 16.70     $ (20,718,957 )
2023   $ 1,333,401     $ 729,761     $ 994,690     $ 734,380     $ 20.37     $ (28,233,242 )
2022   $ 1,106,612     $ 1,011,955     $ 947,391     $ 673,681     $ 28.44     $ (32,812,583 )

 

(1)For years 2024, 2023 and 2022, Dr. Phillip P. Chan has been our Principal Executive Officer. The averages for year 2024 for our Non-PEO Named Executive Officers consist of our President and Chief Operating Officer (Vincent J. Capponi), our Chief Financial Officer (Kathleen P. Bloch from January 1, 2024 to August 13, 2024 and Peter J. Mariani from August 14, 2024 to December 31, 2024, and our Chief Medical Officer (Efthymios, N. Deliargyris). The averages for 2023 and 2022 for our Non-PEO Named Executive Officers consists of Vincent J. Capponi, Kathleen P. Bloch, and Efthymios, N. Deliargyris.

 

(2)Adjustment to Compensation Actually Paid to PEO include deduction of “stock awards” and “options awards” for the year, which include a) add award granted in the year that remain outstanding and unvested at fair value as of end of the year, b) add award granted in the year that vested in the same year at fair value as of the vesting date, c) add or subtract (if negative) any award granted before the year and remain outstanding and unvested as of year-end at fair value, d) add or subtract (if negative) any award granted before the year but vested during the year at fair value as of the vesting date, e)subtract any award vested and forfeited at fair value as of end of the prior year, f) add unvested award on which dividends or other earnings were paid during the year not otherwise included in summary total compensation column.

 

(3)Adjustment to Average Compensation Actually Paid to Non-PEO Named Executive Officers

 

 

   Adjustment to Determine Compensation
“Actually Paid” to PEO		 
   2024   2023   2022 
Deduction for Amounts Reported under the “Stock Awards” Column in the SCT   (91,680)   (307,110)   (154,050)
Deduction for Amounts Reported under the “Option Awards” Column in the SCT   (169,888)   (374,514)   (410,633)
Increase for Fair Value of Awards Granted During the Year that Remain Unvested as of Year-end   144,361    188,015    451,693 
Increase for Fair Value of Awards Granted During the Year that Vested During the Year   —    —    82,800 
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Current Year-end of Awards Granted Prior to Year that were Outstanding and Unvested as of Year-end   (58,377)   (341,105)   (157,121)
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Vesting Date of Awards Granted Prior to Year that Vested During the Year   229,032    231,073    92,654 
Deduction of Fair Value of Awards Granted Prior to year that were Forfeited during year   —    —    — 
Increase based on Dividends or Other Earnings Paid during year Prior to Vesting Date of Award   —    —    — 
Total Adjustments   53,448    (603,641)   (94,657)
    Adjustment to Determine Compensation
“Actually Paid” to Non-PEO		  
    2024     2023     2022  
Deduction for Amounts Reported under the “Stock Awards” Column in the SCT     (122,274 )     (180,313 )     (114,725 )
Deduction for Amounts Reported under the “Option Awards” Column in the SCT     (244,350 )     (242,195 )     (395,600 )
Increase/(Decrease) for Fair Value of Awards Granted During the Year that Remain Unvested as of Year-end     188,731       130,704       243,834  
Increase for Fair Value of Awards Granted During the Year that Vested During the Year     —       20,886       61,482  
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Current Year-end of Awards Granted Prior to Year that were Outstanding and Unvested as of Year-end     (106,288 )     (164,467 )     (133,662 )
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Vesting Date of Awards Granted Prior to Year that Vested During the Year     159,261       175,076       64,961  
Deduction of Fair Value of Awards Granted Prior to year that were Forfeited during year     —       —       —  
Increase based on Dividends or Other Earnings Paid during year Prior to Vesting Date of Award     —       —       —  
Total Adjustments     (124,920 )     (260,309 )     (273,710 )
    
Named Executive Officers, Footnote
(1)For years 2024, 2023 and 2022, Dr. Phillip P. Chan has been our Principal Executive Officer. The averages for year 2024 for our Non-PEO Named Executive Officers consist of our President and Chief Operating Officer (Vincent J. Capponi), our Chief Financial Officer (Kathleen P. Bloch from January 1, 2024 to August 13, 2024 and Peter J. Mariani from August 14, 2024 to December 31, 2024, and our Chief Medical Officer (Efthymios, N. Deliargyris). The averages for 2023 and 2022 for our Non-PEO Named Executive Officers consists of Vincent J. Capponi, Kathleen P. Bloch, and Efthymios, N. Deliargyris.
    
PEO Total Compensation Amount $ 899,695 $ 1,333,401 $ 1,106,612
PEO Actually Paid Compensation Amount $ 953,144 729,761 1,011,955
Adjustment To PEO Compensation, Footnote
(2)Adjustment to Compensation Actually Paid to PEO include deduction of “stock awards” and “options awards” for the year, which include a) add award granted in the year that remain outstanding and unvested at fair value as of end of the year, b) add award granted in the year that vested in the same year at fair value as of the vesting date, c) add or subtract (if negative) any award granted before the year and remain outstanding and unvested as of year-end at fair value, d) add or subtract (if negative) any award granted before the year but vested during the year at fair value as of the vesting date, e)subtract any award vested and forfeited at fair value as of end of the prior year, f) add unvested award on which dividends or other earnings were paid during the year not otherwise included in summary total compensation column.
   Adjustment to Determine Compensation
“Actually Paid” to PEO		 
   2024   2023   2022 
Deduction for Amounts Reported under the “Stock Awards” Column in the SCT   (91,680)   (307,110)   (154,050)
Deduction for Amounts Reported under the “Option Awards” Column in the SCT   (169,888)   (374,514)   (410,633)
Increase for Fair Value of Awards Granted During the Year that Remain Unvested as of Year-end   144,361    188,015    451,693 
Increase for Fair Value of Awards Granted During the Year that Vested During the Year   —    —    82,800 
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Current Year-end of Awards Granted Prior to Year that were Outstanding and Unvested as of Year-end   (58,377)   (341,105)   (157,121)
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Vesting Date of Awards Granted Prior to Year that Vested During the Year   229,032    231,073    92,654 
Deduction of Fair Value of Awards Granted Prior to year that were Forfeited during year   —    —    — 
Increase based on Dividends or Other Earnings Paid during year Prior to Vesting Date of Award   —    —    — 
Total Adjustments   53,448    (603,641)   (94,657)
    
Non-PEO NEO Average Total Compensation Amount $ 895,556 994,690 947,391
Non-PEO NEO Average Compensation Actually Paid Amount $ 770,636 734,380 673,681
Adjustment to Non-PEO NEO Compensation Footnote
(3)Adjustment to Average Compensation Actually Paid to Non-PEO Named Executive Officers
    Adjustment to Determine Compensation
“Actually Paid” to Non-PEO		  
    2024     2023     2022  
Deduction for Amounts Reported under the “Stock Awards” Column in the SCT     (122,274 )     (180,313 )     (114,725 )
Deduction for Amounts Reported under the “Option Awards” Column in the SCT     (244,350 )     (242,195 )     (395,600 )
Increase/(Decrease) for Fair Value of Awards Granted During the Year that Remain Unvested as of Year-end     188,731       130,704       243,834  
Increase for Fair Value of Awards Granted During the Year that Vested During the Year     —       20,886       61,482  
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Current Year-end of Awards Granted Prior to Year that were Outstanding and Unvested as of Year-end     (106,288 )     (164,467 )     (133,662 )
Increase/(Decrease) for Change in Fair Value from Prior Year-end to Vesting Date of Awards Granted Prior to Year that Vested During the Year     159,261       175,076       64,961  
Deduction of Fair Value of Awards Granted Prior to year that were Forfeited during year     —       —       —  
Increase based on Dividends or Other Earnings Paid during year Prior to Vesting Date of Award     —       —       —  
Total Adjustments     (124,920 )     (260,309 )     (273,710 )
    
Compensation Actually Paid vs. Total Shareholder Return

   
Compensation Actually Paid vs. Net Income

   
Total Shareholder Return Amount $ 16.7 20.37 28.44
Net Income (Loss) $ (20,718,957) (28,233,242) (32,812,583)
PEO Name Dr. Phillip P. Chan    
PEO | Equity Awards Adjustments      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ 53,448 (603,641) (94,657)
PEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 144,361 188,015 451,693
PEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (58,377) (341,105) (157,121)
PEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 82,800
PEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 229,032 231,073 92,654
PEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount
PEO | Stock Awards Value In Compensation Table For The Applicable Year Member      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (91,680) (307,110) (154,050)
PEO | Option Awards Value In Compensation Table For The Applicable Year Member      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (169,888) (374,514) (410,633)
PEO | Equity Awards Adjustments Change In Fair Value Of Awards Granted In Prior Years Forfeited During Current Year [Member]      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount
Non-PEO NEO | Equity Awards Adjustments      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (124,920) (260,309) (273,710)
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 188,731 130,704 243,834
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (106,288) (164,467) (133,662)
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 20,886 61,482
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 159,261 175,076 64,961
Non-PEO NEO | Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount
Non-PEO NEO | Stock Awards Value In Compensation Table For The Applicable Year Member      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (122,274) (180,313) (114,725)
Non-PEO NEO | Option Awards Value In Compensation Table For The Applicable Year Member      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (244,350) (242,195) (395,600)
Non-PEO NEO | Equity Awards Adjustments Change In Fair Value Of Awards Granted In Prior Years Forfeited During Current Year [Member]      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount