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Stockholders’ Equity (Tables) | 12 Months Ended
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Dec. 31, 2021
Equity [Abstract] |
Summary of Changes in Warrants Outstanding | The following is a summary of changes in warrants outstanding for the years ended December 31, 2021 and 2020: Summary of Changes in Warrants Outstanding
|  | Number of warrants |
Outstanding at December 31,2019 |  |  | 2,014,694 |
Issued |  |  | 655,763 |
Expired |  |  | (466,154 | )
Outstanding at December 31, 2020 |  |  | 2,204,303 |
Issued |  |  | 10,550 |
Expired |  |  | (927,449 | )
Outstanding at December 31, 2021 |  |  | 1,287,404 |
Summary of Outstanding Warrants | The following is a summary of all outstanding warrants as of December 31, 2021: Summary of Outstanding Warrants
Warrant issuance event |  | Number of warrants |  |  | Weighted average exercise price |  |  | Exercise price per share |  |  | Remaining term in years |  |  | Intrinsic value at date of grant |
Private placements of common stock |  |  | 818,683 |  |  | $ | 7.65 |  |  | $ | 6.89 - 7.80 |  |  |  | 1.28 |  |  | $ | - |
Private placement of notes |  |  | 214,356 |  |  | $ | 8.39 |  |  | $ | 7.80 - 9.10 |  |  |  | 0.76 |  |  | $ | - |
Settlement of deferred compensation |  |  | 243,815 |  |  | $ | 6.32 |  |  | $ | 3.51 - 9.10 |  |  |  | 2.74 |  |  | $ | - |
Settlement of services |  |  | 10,550 |  |  | $ | 4.15 |  |  | $ | 3.12 - 5.46 |  |  |  | 0.62 |  |  | $ | - |
|  |  | 1,287,404 |  |  | $ | 7.49 |  |  | $ | 3.12 - 9.10 |  |  |  | 1.47 |  |  | $ | - |
Summary of Stock Options Activity | The following summarizes activity related to stock options for the years ended December 31, 2021 and 2020: Summary of Stock Options Activity
|  | Number of Options |  |  | Exercise price per share |  |  | Remaining term in years |
Outstanding January 1, 2020 |  |  | 554,076 |  |  |  | $5.20 - $11.31 |  |  |  | 4.6 |
Issued |  |  | 82,258 |  |  |  | $4.42 - $5.72 |  |  |  |  |
Cancelled/expired |  |  | (48,109 | ) |  |  |  |  |  |  |  |
Outstanding on December 31, 2020 |  |  | 588,225 |  |  |  | $4.42 - $11.31 |  |  |  | 3.5 |
Issued |  |  | 58,113 |  |  |  | $4.94 - $6.37 |  |  |  |  |
Cancelled/expired |  |  | (44,187 | ) |  |  |  |  |  |  |  |
Outstanding on December 31, 2021 |  |  | 602,151 |  |  |  | $4.42 - $11.31 |  |  |  | 3.8 |
Exercisable, December 31, 2021 |  |  | 513,416 |  |  |  | $4.42 - $11.31 |  |  |  | 3.3 |
Summary of Fair Value of Options Using Black-Sholes Option Pricing Model | The fair value of the options issued was calculated using the Black-Sholes option pricing model, based on the criteria shown below: Summary of Fair Value of Options Using Black-Sholes Option Pricing Model
|  | 2021 |  |  | 2020 |
Expected term (in years) |  |  | 5.5 - 8.0 |  |  |  | 5.5 - 8.0 |
Expected volatility |  |  | 85.0% - 89.4 | % |  |  | 73.4% - 75.8 | %
Risk-free interest rate |  |  | 0.7% - 1.3 | % |  |  | 0.3% - 1.6% |
Expected dividends |  | $ | - |  |  | $ | - |
Weighted average grant date fair value per share |  | $ | 4.04 |  |  | $ | 2.65 |

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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section S99 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6784392&loc=d3e188667-122775 + Details
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