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License and Distribution Agreements - Additional Information (Details) - USD ($) $ in Thousands |  |  |  |  |  |  | 12 Months Ended
--- | --- | --- | --- | --- | --- | --- | ---
Dec. 11, 2023 | Aug. 25, 2023 | Apr. 13, 2023 | Mar. 17, 2023 | Sep. 01, 2021 | May 07, 2021 | Dec. 31, 2023 | Dec. 31, 2022
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Issuance of common stock |  |  |  |  |  |  | $ 136 | $ 6,021
Common Stock |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Purchase and sale of shares |  |  |  |  |  |  | 13,296 | 265,641
Arthrex Agreement |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Supply and distribution agreement period |  |  |  |  |  | 6 years |  |
Supply and distribution agreement renewal term |  |  |  |  |  | 2 years |  |
Supply and distribution agreement non-renewal notice period |  |  |  |  |  | 12 months |  |
Discount percentage, payment for invoices within ten days |  |  |  |  |  | 2.00% |  |
Payment term, net |  |  |  |  |  | 45 days |  |
Material breach, contract terminated term |  |  |  |  |  | 30 days |  |
Evolution Agreement |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Outstanding invoice amount refused |  |  | $ 2,350 |  |  |  |  |
Supply and distribution agreement period |  |  |  |  | 3 years |  |  |
Agreement termination date |  |  | Apr. 13, 2023 |  |  |  |  |
Regeneron Research Collaboration Services Agreement |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Notice period |  | 30 days |  |  |  |  |  |
Service agreement term |  | 5 years |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  | $ 750 |
Pulthera, LLC Binding Term Sheet |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Payment of option fee in cash |  |  |  |  |  |  | 3,000 |
Pulthera, LLC Binding Term Sheet | Research and Development Expense |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Option fee included in research and development expense |  |  |  |  |  |  | 3,000 |
Pulthera, LLC Binding Term Sheet | Common Stock |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
Issuance of common stock |  |  |  |  |  |  | $ 1,000 |
Purchase and sale of shares |  |  |  | 169,492 |  |  |  |
License Agreement with BioCellgraft, Inc. |  |  |  |  |  |  |  |
License And Distribution Agreements [Line Items] |  |  |  |  |  |  |  |
License fee expense | $ 5,000 |  |  |  |  |  |  |
License fee payment | $ 300 |  |  |  |  |  |  |
Commercial license to dental products agreement initial period | 4 years |  |  |  |  |  |  |
Commercial license to dental products agreement renewal term | 2 years |  |  |  |  |  |  |
License fees payment period | 2 years |  |  |  |  |  |  |

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