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Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Total | PIPE Investors | Registered Direct Offering | Pulthera Llc | CV Star Loan | Cumulative Effect, Period of Adoption, Adjustment | Common Stock | Common Stock PIPE Investors | Common Stock Registered Direct Offering | Common Stock Pulthera Llc | Additional Paid-in Capital | Additional Paid-in Capital PIPE Investors | Additional Paid-in Capital Registered Direct Offering | Additional Paid-in Capital Pulthera Llc | Additional Paid-in Capital CV Star Loan | Accumulated Deficit | Accumulated Deficit Cumulative Effect, Period of Adoption, Adjustment | Accumulated Other Comprehensive Income
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2021 | $ 99,418 |  |  |  |  |  | $ 12 |  |  |  | $ 763,087 |  |  |  |  | $ (663,681) |  |
Balance (Accounting Standards Update 2016-02) at Dec. 31, 2021 |  |  |  |  |  | $ 3,993 |  |  |  |  |  |  |  |  |  |  | $ 3,993 |
Balance (in Shares) at Dec. 31, 2021 |  |  |  |  |  |  | 12,430,788 |  |  |  |  |  |  |  |  |  |  |
Reclassification of previously exercised stock options | 441 |  |  |  |  |  |  |  |  |  | 441 |  |  |  |  |  |  |
Reclassification of previously exercised stock options, in shares |  |  |  |  |  |  | 13,125 |  |  |  |  |  |  |  |  |  |  |
Exercise of stock options | 948 |  |  |  |  |  |  |  |  |  | 948 |  |  |  |  |  |  |
Exercise of stock options (in Shares) |  |  |  |  |  |  | 171,047 |  |  |  |  |  |  |  |  |  |  |
Purchase and retirement of common shares | (86) |  |  |  |  |  |  |  |  |  | (86) |  |  |  |  |  |  |
Purchase and retirement of common shares, in shares |  |  |  |  |  |  | (1,050) |  |  |  |  |  |  |  |  |  |  |
Exercise of warrants | 46,491 |  |  |  |  |  | $ 2 |  |  |  | 46,489 |  |  |  |  |  |  |
Exercise of warrants, in shares |  |  |  |  |  |  | 1,328,189 |  |  |  |  |  |  |  |  |  |  |
Common stock issued pursuant to short-term debt conversion | 4,088 |  |  |  |  |  | $ 1 |  |  |  | 4,098 |  |  |  |  |  |  | $ (11)
Common stock issued pursuant to short-term debt conversion, in shares |  |  |  |  |  |  | 262,797 |  |  |  |  |  |  |  |  |  |  |
Vesting of restricted stock units, in shares |  |  |  |  |  |  | 23,252 |  |  |  |  |  |  |  |  |  |  |
Vesting of restricted stock units | 0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Tax withholding on vesting of restricted stock units | (132) |  |  |  |  |  |  |  |  |  | (132) |  |  |  |  |  |  |
Tax withholding on vesting of restricted stock units, in shares |  |  |  |  |  |  | (7,067) |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation expense | 15,856 |  |  |  |  |  |  |  |  |  | 15,856 |  |  |  |  |  |  |
Issuance of common stock | 6,021 | $ 7,651 |  |  |  |  |  |  |  |  | 6,021 | $ 7,651 |  |  |  |  |  |
Issuance of common stock (in Shares) |  |  |  |  |  |  | 265,641 | 405,406 |  |  |  |  |  |  |  |  |  |
Change in fair value of debt due to change in credit risk, net of tax | 20 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 20
Net income (loss) | 14,192 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 14,192 |  |
Balance at Dec. 31, 2022 | 198,901 |  |  |  |  |  | $ 15 |  |  |  | 844,373 |  |  |  |  | (645,496) |  | 9
Balance (in Shares) at Dec. 31, 2022 |  |  |  |  |  |  | 14,892,129 |  |  |  |  |  |  |  |  |  |  |
Fair value of warrant modification for professional services | 403 |  |  |  |  |  |  |  |  |  | 403 |  |  |  |  |  |  |
Common stock issued pursuant to short-term debt maturity extension, shares |  |  |  |  |  |  | 270,731 |  |  |  |  |  |  |  |  |  |  |
Common stock issued pursuant to short-term debt maturity extension | 712 |  |  |  |  |  |  |  |  |  | 712 |  |  |  |  |  |  |
Exercise of stock options | 304 |  |  |  |  |  |  |  |  |  | 304 |  |  |  |  |  |  |
Exercise of stock options (in Shares) |  |  |  |  |  |  | 108,637 |  |  |  |  |  |  |  |  |  |  |
Common stock issued pursuant to short-term debt conversion | 4,444 |  |  |  |  |  | $ 1 |  |  |  | 4,598 |  |  |  |  |  |  | (155)
Common stock issued pursuant to short-term debt conversion, in shares |  |  |  |  |  |  | 559,481 |  |  |  |  |  |  |  |  |  |  |
Vesting of restricted stock units, in shares |  |  |  |  |  |  | 83,759 |  |  |  |  |  |  |  |  |  |  |
Vesting of restricted stock units | 0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Tax withholding on vesting of restricted stock units | (101) |  |  |  |  |  |  |  |  |  | (101) |  |  |  |  |  |  |
Tax withholding on vesting of restricted stock units, in shares |  |  |  |  |  |  | (19,130) |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation expense | 15,017 |  |  |  |  |  |  |  |  |  | 15,017 |  |  |  |  |  |  |
Issuance of warrants | 2,016 |  |  |  | $ 274 |  |  |  |  |  | 2,016 |  |  |  | $ 274 |  |  |
Issuance of common stock | 136 | $ 12,681 | $ 1,322 | $ 1,000 |  |  |  | $ 1 | $ 2 |  | 136 | $ 12,680 | $ 1,320 | $ 1,000 |  |  |  |
Issuance of common stock (in Shares) |  |  |  |  |  |  | 13,296 | 1,519,579 | 1,780,220 | 169,492 |  |  |  |  |  |  |  |
Change in fair value of debt due to change in credit risk, net of tax | 146 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 146
Net income (loss) | (196,295) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (196,295) |  |
Balance at Dec. 31, 2023 | $ 40,960 |  |  |  |  |  | $ 19 |  |  |  | $ 882,732 |  |  |  |  | $ (841,791) |  | $ 0
Balance (in Shares) at Dec. 31, 2023 |  |  |  |  |  |  | 19,378,192 |  |  |  |  |  |  |  |  |  |  |

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