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Segment Information | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Segment Information | 11. Segment Information The Company manages its operations as a single operating and reportable segment focused on the research and development of precision oncology therapies. The accounting policies of the single reportable segment are identical to those described in Note 2. The chief operating decision maker, who manages the Company’s operations on a consolidated basis, assesses performance for the reportable segment using consolidated net loss to monitor budget versus actual results and to determine how to effectively allocate the Company’s resources. The measure of segment assets is reported on the consolidated balance sheets as total consolidated assets. The following table presents certain financial data including significant segment expenses for the Company’s reportable segment for the three and nine months ended September 30, 2025 and 2024 (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
ACR-368 direct research and development expenses |  | $ | 3,985 |  |  | $ | 11,098 |  |  | $ | 17,645 |  |  | $ | 24,097 |
ACR-2316 direct research and development expenses 1 |  |  | 2,628 |  |  |  | 1,735 |  |  |  | 5,558 |  |  |  | 1,735 |
Other drug discovery programs direct research and development expenses |  |  | 496 |  |  |  | 368 |  |  |  | 1,705 |  |  |  | 3,490 |
Personnel related indirect research and development expenses |  |  | 5,215 |  |  |  | 4,510 |  |  |  | 16,367 |  |  |  | 13,031 |
Facilities, supplies and other indirect research and development expenses |  |  | 1,324 |  |  |  | 1,153 |  |  |  | 3,969 |  |  |  | 3,009 |
General and administrative expenses |  |  | 6,039 |  |  |  | 6,276 |  |  |  | 18,754 |  |  |  | 18,883 |
Other segment items 2 |  |  | (1,453 | ) |  |  | (2,699 | ) |  |  | (5,078 | ) |  |  | (6,520 | )
Net loss |  | $ | (18,234 | ) |  | $ | (22,441 | ) |  | $ | (58,920 | ) |  | $ | (57,725 | )
1 ACR-2316 direct research and development expenses include costs related to the Company’s novel, internally-discovered second clinical stage asset, which was promoted to a development program upon being granted IND clearance in the third quarter of 2024 and includes clinical trial and related activities. Prior to IND clearance, costs related to preclinical drug discovery activities progression related to ACR-2316 were included in other drug discovery programs direct research and development expenses. 2 Other segment items consist of interest income and other (expense) income, net. Interest income consists of interest income earned on cash equivalents and investments and amortization of premiums and accretion of discounts to maturity for available-for-sale debt securities. Other (expense) income, net primarily consists of realized and unrealized gains and losses on foreign currency transactions, state taxes, and investment management fees.

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- Definition The entire disclosure for reporting segments including data and tables. 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