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Nature of the Business and Operations (Details) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 12 Months Ended
Oct. 13, 2015
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Nature of the Business and Operations [Line Items]                                
Net loss (including noncontrolling interests)   $ (2,588) $ (1,368) $ (1,792) $ (2,072) $ (3,107) $ (3,245) $ (3,874) $ (4,008) $ (3,047) $ (3,343) $ (3,120) $ (3,570) $ (7,820) $ (14,234) $ (13,080)
Accumulated deficit   $ (173,749)       $ (165,929)               (173,749) (165,929)  
Net cash used in operating activities                           $ (8,063) $ (11,824) $ (8,801)
Issuance of common stock 3,200,000 1,800,000                            
Price per share $ 1.90                              
Stock issued for cash $ 6,100                              
Cash 5,400                              
Direct offering cost $ 700