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Stockholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2017
Stockholders Equity (Textual) |
Summary of all warrant activity |
Outstanding and exercisable |  | Warrants |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Life |
January 1, 2015 |  |  | 3,335,073 |  |  | $ | 4.45 |  |  |  | 0.93 |
Issued |  |  | - |  |  |  | - |  |  |  | - |
Expired/forfeited |  |  | (2,591,000 | ) |  |  | 5.06 |  |  |  | - |
Exercised |  |  | (280,000 | ) |  |  | 1.30 |  |  |  | - |
December 31, 2015 |  |  | 464,073 |  |  | $ | 3.02 |  |  |  | 0.19 |
Issued |  |  | 3,600,000 |  |  |  | 0.01 |  |  |  | - |
Issued (Prefunded) |  |  | 4,313,676 |  |  |  | 1.12 |  |  |  | - |
Expired/forfeited |  |  | (384,073 | ) |  |  | 3.13 |  |  |  | - |
Exercised |  |  | (80,000 | ) |  |  | 2.00 |  |  |  | - |
December 31, 2016 |  |  | 7,913,676 |  |  | $ | 0.62 |  |  |  | 5.13 |
Issued (Purchase) |  |  | 3,250,001 |  |  |  | 2.00 |  |  |  | - |
Expired/forfeited |  |  | - |  |  |  | - |  |  |  | - |
Exercised |  |  | - |  |  |  | - |  |  |  | - |
Outstanding, December 31, 2017 |  |  | 11,163,677 |  |  | $ | 1.02 |  |  |  | 3.68 |
Outstanding and exercisable, December 31, 2017 |  |  | 7,913,676 |  |  | $ | 0.62 |  |  |  | 4.13 |
Schedule of conversion of preferred stock issued to common stock |
|  | Shares of Preferred Stock Not Exchanged as of December 31, 2017 |  |  | Conversion Ratio |  |  | Shares of Common Stock after Conversion of all Outstanding Shares of Preferred Stock Not yet Exchanged at December 31, 2017 |
Series B Preferred Stock |  |  | 83 |  |  |  | 132.07 |  |  |  | 10,962 |
Warrant [Member] |
Stockholders Equity (Textual) |
Summary of all stock option plans / warrant activity |
Description |  | Issue Date |  | Exercise Price |  |  | Shares |  |  | Expiration Date
August 2016 Prefunded Warrants |  | 08/16/16 |  | $ | 1.00 |  |  |  | 3,600,000 |  |  | 02/16/22
August 2016 Purchase Warrants |  | 08/17/16 |  | $ | 1.12 |  |  |  | 4,313,676 |  |  | 02/17/22
August 2017 Purchase Warrants |  | 08/08/17 |  | $ | 2.00 |  |  |  | 3,250,001 |  |  | 08/08/20
Total Warrants Outstanding |  |  |  |  |  |  |  |  | 11,163,677 |  |  |

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