    <SEC-DOCUMENT>0001640334-18-001822-index.html : 20190225
    <SEC-HEADER>0001640334-18-001822.hdr.sgml : 20190225

    <ACCEPTANCE-DATETIME>20180926173119

    <PRIVATE-TO-PUBLIC>

    ACCESSION NUMBER:		0001640334-18-001822

    CONFORMED SUBMISSION TYPE:	S-1/A

    PUBLIC DOCUMENT COUNT:		18

    FILED AS OF DATE:		20180926

    DATE AS OF CHANGE:		20181219

    FILER:

    	COMPANY DATA:

    		COMPANY CONFORMED NAME:			Inmune Bio, Inc.

    		CENTRAL INDEX KEY:			0001711754

    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]

    		IRS NUMBER:				475205835

    		STATE OF INCORPORATION:			NV

    		FISCAL YEAR END:			1231

    	FILING VALUES:

    		FORM TYPE:		S-1/A

    		SEC ACT:		1933 Act

    		SEC FILE NUMBER:	333-227122

    		FILM NUMBER:		181088727

    	BUSINESS ADDRESS:

    		STREET 1:		1224 PROSPECT STREET

    		STREET 2:		SUITE 150

    		CITY:			LA JOLLA

    		STATE:			CA

    		ZIP:			92037

    		BUSINESS PHONE:		8589643720

    	MAIL ADDRESS:

    		STREET 1:		1224 PROSPECT STREET

    		STREET 2:		SUITE 150

    		CITY:			LA JOLLA

    		STATE:			CA

    		ZIP:			92037

    </SEC-HEADER>

    <DOCUMENT>
    <TYPE>S-1/A
    <SEQUENCE>1
    <FILENAME>inmune_s1a1.htm
    <DESCRIPTION>FORM S-1 AMENDMENT NO. 1
    <TEXT>
    Document 1 - file: inmune_s1a1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-1.1
    <SEQUENCE>2
    <FILENAME>inmune_ex11.htm
    <DESCRIPTION>EX-1.1
    <TEXT>
    Document 2 - file: inmune_ex11.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.1
    <SEQUENCE>3
    <FILENAME>immune_ex41.htm
    <DESCRIPTION>EX-4.1
    <TEXT>
    Document 3 - file: immune_ex41.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.2
    <SEQUENCE>4
    <FILENAME>inmune_ex42.htm
    <DESCRIPTION>EX-4.2
    <TEXT>
    Document 4 - file: inmune_ex42.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.2
    <SEQUENCE>5
    <FILENAME>inmune_ex1021.htm
    <DESCRIPTION>EX-10.21
    <TEXT>
    Document 5 - file: inmune_ex1021.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.21
    <SEQUENCE>6
    <FILENAME>inmune_ex1022.htm
    <DESCRIPTION>EX-10.22
    <TEXT>
    Document 6 - file: inmune_ex1022.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.2
    <SEQUENCE>7
    <FILENAME>inmune_ex232.htm
    <DESCRIPTION>EX-23.2
    <TEXT>
    Document 7 - file: inmune_ex232.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>immune_ex41img2.jpg
    <TEXT>
    Document 9 - file: immune_ex41img2.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>immune_ex41img5.jpg
    <TEXT>
    Document 10 - file: immune_ex41img5.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>inmune_correspimg1.jpg
    <TEXT>
    Document 11 - file: inmune_correspimg1.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>inmune_s1img1.jpg
    <TEXT>
    Document 12 - file: inmune_s1img1.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>inmune_s1img10.jpg
    <TEXT>
    Document 13 - file: inmune_s1img10.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>inmune_s1img11.jpg
    <TEXT>
    Document 14 - file: inmune_s1img11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>inmune_s1img12.jpg
    <TEXT>
    Document 15 - file: inmune_s1img12.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>inmune_s1img13.jpg
    <TEXT>
    Document 16 - file: inmune_s1img13.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>inmune_s1img14.jpg
    <TEXT>
    Document 17 - file: inmune_s1img14.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>inmune_s1img9.jpg
    <TEXT>
    Document 18 - file: inmune_s1img9.jpg

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    <DOCUMENT>
    <TYPE>CORRESP
    <SEQUENCE>19
    <FILENAME>filename19.htm
    <TEXT>
    Document 19 - file: filename19.htm

    </DOCUMENT>
    </SEC-DOCUMENT>