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United States securities and exchange commission logo





                          September 13, 2021

       David Moss
       Chief Financial Officer
       Inmune Bio, Inc.
       980 North Federal Highway, Suite 110
       Boca Raton, FL 33432

                                                        Re: Inmune Bio, Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed September 7,
2021
                                                            File No. 333-259368

       Dear Mr. Moss:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Alan
Campbell at 202-551-4224 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              David B. Manno, Esq.
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