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Property, Plant and Equipment (Details) - USD ($) | 3 Months Ended |
--- | --- | ---
Mar. 31, 2017 | Dec. 31, 2016
Property, Plant and Equipment [Line Items] |  |  |
Laboratory and manufacturing equipment |  | $ 5,360,730 | $ 5,562,938
Building and improvements |  | 5,373,019 | 5,037,512
Office furniture and equipment |  | 655,022 | 653,462
Construction in progress | [1] | 7,481,083 | 3,694,509
Land |  | 526,998 | 347,114
Property, plant and equipment, gross |  | 19,396,852 | 15,295,535
Accumulated depreciation |  | (5,272,074) | (5,449,242)
Property, plant and equipment, net |  | 14,124,778 | $ 9,846,293
(Decrease) Increase in Property, plant and equipment, gross |  | 4,101,317 |
(Decrease) Increase in Accumulated depreciation |  | 177,168 |
(Decrease) Increase in Property, plant and equipment, net |  | 4,278,485 |
Laboratory and manufacturing equipment [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
(Decrease) Increase in Property, plant and equipment, gross |  | $ (202,208) |
Laboratory and manufacturing equipment [Member] | Maximum [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, plant and equipment, Estimated Useful Lives |  | 10 years |
Laboratory and manufacturing equipment [Member] | Minimum [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, plant and equipment, Estimated Useful Lives |  | 5 years |
Building and improvements [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
(Decrease) Increase in Property, plant and equipment, gross |  | $ 335,507 |
Building and improvements [Member] | Maximum [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, plant and equipment, Estimated Useful Lives |  | 33 years |
Building and improvements [Member] | Minimum [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, plant and equipment, Estimated Useful Lives |  | 10 years |
Office furniture and equipment [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
(Decrease) Increase in Property, plant and equipment, gross |  | $ 1,560 |
Office furniture and equipment [Member] | Maximum [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, plant and equipment, Estimated Useful Lives |  | 10 years |
Office furniture and equipment [Member] | Minimum [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
Property, plant and equipment, Estimated Useful Lives |  | 5 years |
Construction in progress [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
(Decrease) Increase in Property, plant and equipment, gross | [1] | $ 3,786,574 |
Land [Member] |  |  |
Property, Plant and Equipment [Line Items] |  |  |
(Decrease) Increase in Property, plant and equipment, gross |  | $ 179,884 |
[1] | Construction in progress consisted principally of costs incurred in connection with the building and equipping of our Nisin production plant for Mast Out®.

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- Definition Amount of increase (decrease) of long-lived, physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment. + References No definition available. + Details
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- Definition Amount before accumulated depreciation of building structures held for productive use including addition, improvement, or renovation to the structure, including, but not limited to, interior masonry, interior flooring, electrical, and plumbing. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 4 -Subparagraph (f) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6812-107765 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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- Definition Amount before accumulated depreciation of equipment commonly used in offices and stores that have no permanent connection to the structure of a building or utilities. Examples include, but are not limited to, desks, chairs, tables, and bookcases. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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- Definition Amount before accumulated depreciation of tangible personal property used to produce goods and services, including, but is not limited to, tools, dies and molds, computer and office equipment. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 4 -Subparagraph (f) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6812-107765 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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