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Income Taxes (Details 1) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Taxes [Abstract]    
Computed expected tax benefit $ (390,610) $ (149,083)
State income taxes, net of federal expense 136,843 30,089
Share-based compensation 67,181 55,955
Tax credits (602,813) (137,983)
Deferred tax statutory rate change (71,034)
Valuation allowance 1,241,007
Other 10,012 1,723
Income tax expense (benefit) $ 461,620 $ (270,333)
Computed expected tax benefit, rate (21.00%) (34.00%)
State income taxes, net of federal expense, rate 7.36% 6.86%
Share-based compensation, rate 3.61% 12.76%
Tax credits, rate (32.41%) (31.47%)
Deferred tax statutory rate change, rate (16.20%)
Valuation allowance, rate 66.72%
Other, rate 0.54% 0.40%
Income tax expense (benefit), rate 24.82% (61.65%)