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Property, Plant and Equipment, Net (Tables)
3 Months Ended
Mar. 31, 2019
Property, Plant and Equipment [Abstract]  
Schedule of property, plant and equipment
   Estimated Useful Lives
(in years)
  As of
March 31,
2019
   As of
December 31,
2018
 
Buildings and improvements  10-39  $17,060,316   $17,018,316 
Laboratory and manufacturing equipment  3-10   15,156,622    15,092,252 
Office furniture and equipment  3-10   733,159    731,510 
Construction in progress  n/a   102,926    91,067 
Land  n/a   516,867    516,867 
Property, plant and equipment, gross      33,569,890    33,450,012 
Accumulated depreciation      (7,984,438)   (7,422,463)
Property, plant and equipment, net     $25,585,452   $26,027,549