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Property, Plant and Equipment, Net | 6 Months Ended
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Jun. 30, 2022
Property, Plant and Equipment [Abstract] |
PROPERTY, PLANT AND EQUIPMENT, net | 7. PROPERTY, PLANT AND EQUIPMENT, net Property, plant and equipment consisted of the following:
|  | Estimated Useful Lives (in years) |  | As of June 30, 2022 |  |  | As of December 31, 2021 |
Laboratory and manufacturing equipment |  | 3-10 |  | $ | 17,989,355 |  |  | $ | 17,388,757 |
Buildings and improvements |  | 10-39 |  |  | 19,339,380 |  |  |  | 19,119,698 |
Office furniture and equipment |  | 3-10 |  |  | 887,559 |  |  |  | 869,191 |
Construction in progress |  | n/a |  |  | 3,876,393 |  |  |  | 2,992,359 |
Land |  | n/a |  |  | 516,867 |  |  |  | 516,867 |
Property, plant and equipment, gross |  |  |  |  | 42,609,554 |  |  |  | 40,886,872 |
Accumulated depreciation |  |  |  |  | (15,191,424 | ) |  |  | (13,993,273 | )
Property, plant and equipment, net |  |  |  | $ | 27,418,130 |  |  | $ | 26,893,599 |
As of June 30, 2022 and December 31, 2021, construction in progress consisted principally of payments toward the First Defense® production capacity expansion project and equipment needed to bring the formulation and aseptic filling for Re-Tain® in-house. Property, plant and equipment disposals were $3,894 and $2,928 during the three-month periods ended June 30, 2022 and 2021, respectively, and $43,305 and $95,049 during the six-month periods ended June 30, 2022 and 2021, respectively. Depreciation expense was $624,609 and $617,527 during the three-month periods ended June 30, 2022 and 2021, respectively, and $1,241,455 and $1,232,222 during the six-month periods ended June 30, 2022 and 2021, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 6 -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99893-112916 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -URI https://asc.fasb.org/topic&trid=2155823 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 7 -URI https://asc.fasb.org/extlink&oid=126982197&loc=SL120174063-112916 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 1 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99779-112916 + Details
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