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Note 6 - Property, Plant and Equipment, Net | 9 Months Ended
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Sep. 30, 2025
Notes to Financial Statements |
Property, Plant and Equipment Disclosure [Text Block] | 6. PROPERTY, PLANT AND EQUIPMENT, net Property, plant and equipment consisted of the following:
|  | Estimated Useful Lives |  |  | As of |  |  | As of |
|  | (in years) |  |  | September 30, 2025 |  |  | December 31, 2024 |
Laboratory and manufacturing equipment |  | 3 - 10 |  |  | $ | 20,888,337 |  |  | $ | 21,234,259 |
Buildings and improvements |  | 10 - 39 |  |  |  | 20,960,522 |  |  |  | 20,889,395 |
Office furniture and equipment |  | 3 - 10 |  |  |  | 928,550 |  |  |  | 1,056,145 |
Construction in progress |  | n/a |  |  |  | 2,645,564 |  |  |  | 2,693,904 |
Land |  | n/a |  |  |  | 516,867 |  |  |  | 516,867 |
Property, plant and equipment, gross |  |  |  |  |  | 45,939,840 |  |  |  | 46,390,570 |
Accumulated depreciation |  |  |  |  |  | (21,599,100 | ) |  |  | (21,041,551 | )
Property, plant and equipment, net |  |  |  |  | $ | 24,340,740 |  |  | $ | 25,349,019 |
As of September 30, 2025 and December 31, 2024, construction in progress consisted principally of payments toward the First Defense® production capacity expansion project and equipment needed to bring the formulation and aseptic filling for Re-Tain® in-house. The costs associated with property, plant and equipment disposals were $1,406,194 and $49,652 during the three-month periods ended September 30, 2025 and 2024, respectively, and $1,542,599 and $120,814 during the nine-month periods ended September 30, 2025 and 2024, respectively. Depreciation expense was $674,314 and $670,346 during the three-month periods ended September 30, 2025 and 2024, respectively, and $2,008,958 and $1,999,005 during the nine-month periods ended September 30, 2025 and 2024, respectively.

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