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                                                            October 15, 2024

Jarrett Boon
Chief Executive Officer
Safety Shot, Inc.
1061 E. Indiantown Rd., Ste. 110
Jupiter, FL 33477

        Re: Safety Shot, Inc.
            Amendment No. 1 to Registration Statement on Form S-3
            Filed October 11, 2024
            File No. 333-282315
Dear Jarrett Boon:

     We have reviewed your amended registration statement and have the
following
comments.

        Please respond to this letter by amending your registration statement
and providing
the requested information. If you do not believe a comment applies to your
facts and
circumstances or do not believe an amendment is appropriate, please tell us why
in your
response.

       After reviewing any amendment to your registration statement and the
information
you provide in response to this letter, we may have additional comments. Unless
we note
otherwise, any references to prior comments are to comments in our October 7,
2024 letter.

Amendment No. 1 to Registration Statement on Form S-3
Prospectus Summary, page 3

1.     We note your response to comment 1, including that you plan to conduct
additional
       research studies to assess varying dosages of the Sure Shot Dietary
Supplement
       against body weight, gender and age, examine several current and
proposed
       ingredients with respect to their specific role in reducing BAC and how
they affect the
       enzymatic activity associated with the metabolism of alcohol, and
examine additional
       markers with respect to improving post-alcohol consumption symptoms and
feelings.
       Please discuss the timing for the commencement and completion of these
planned
       studies, and disclose whether you have obtained a sponsor, a location,
and/or have
       begun selecting participants for these studies.
 October 15, 2024
Page 2
2.     We note your response to comment 2 and your statement on page 4: "the
study
       assumed that the participants would feel better and demonstrate marked
improvement
       in cognitive skills and physical function following the consumption of
the Sure Shot
       Dietary Supplement versus that of the placebo." Please further explain
how you
       measured this and the results. Please also further discuss the basis for
this assumption.
       Please also clarify whether you conducted any additional studies or
research, other
       than the clinical trial involving 36 participants, indicating that the
Sure Shot Dietary
       Supplement can reduce a person's BAC. We note your disclosure on page 4
that you
       "have conducted extensive research and experimentation involving a
substantial
       number of volunteers under the influence of alcohol."
Incorporation Of Certain Information By Reference, page 18

3.     We note your response to comment 4. Please revise to incorporate by
reference all of
       the current reports on Form 8-K required pursuant to Item 12(a)(2) of
Form S-3,
       which requires incorporation by reference of all current reports filed
pursuant to
       Section 13(a) or 15(d) of the Exchange Act since the end of the fiscal
year covered by
       the registrant's latest annual report on Form 10-K.
General

4.     We note your response to comment 5. Please discuss the transactions
pursuant to
       which your shares of common stock being registered for resale were
issued,
       including the 350,000 previously issued shares of your common stock that
are not
       currently described.

       Please contact Juan Grana at 202-551-6034 or Margaret Sawicki at
202-551-7153
with any questions.



                                                             Sincerely,

                                                             Division of
Corporation Finance
                                                             Office of
Industrial Applications and
                                                             Services
cc:   Arthur S. Marcus, Esq.
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