<SEC-DOCUMENT>0001225208-12-006674.txt : 20120305
<SEC-HEADER>0001225208-12-006674.hdr.sgml : 20120305
<ACCEPTANCE-DATETIME>20120305174639
ACCESSION NUMBER:		0001225208-12-006674
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20120301
FILED AS OF DATE:		20120305
DATE AS OF CHANGE:		20120305

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			PISARIS JOHN B
		CENTRAL INDEX KEY:			0001306764

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32442
		FILM NUMBER:		12667884

	MAIL ADDRESS:	
		STREET 1:		C/O MIVA, INC.
		STREET 2:		5220 SUMMERLIN COMMONS BLVD., SUITE 500
		CITY:			FORT MYERS
		STATE:			FL
		ZIP:			33907

	FORMER NAME:	
		FORMER CONFORMED NAME:	Pisaris John Boyd
		DATE OF NAME CHANGE:	20041021

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INUVO, INC.
		CENTRAL INDEX KEY:			0000829323
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-ADVERTISING [7310]
		IRS NUMBER:				870450450
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1210

	BUSINESS ADDRESS:	
		STREET 1:		15550 LIGHTWAVE DRIVE
		STREET 2:		THIRD FLOOR
		CITY:			CLEARWATER
		STATE:			FL
		ZIP:			33761
		BUSINESS PHONE:		727-324-0046

	MAIL ADDRESS:	
		STREET 1:		15550 LIGHTWAVE DRIVE
		STREET 2:		THIRD FLOOR
		CITY:			CLEARWATER
		STATE:			FL
		ZIP:			33761

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	KOWABUNGA! INC.
		DATE OF NAME CHANGE:	20081106

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	THINK PARTNERSHIP INC
		DATE OF NAME CHANGE:	20060315

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CGI HOLDING CORP
		DATE OF NAME CHANGE:	19980501
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0304</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2012-03-01</periodOfReport>

    <issuer>
        <issuerCik>0000829323</issuerCik>
        <issuerName>INUVO, INC.</issuerName>
        <issuerTradingSymbol>INUV</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001306764</rptOwnerCik>
            <rptOwnerName>PISARIS JOHN B</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>143 VARICK ST.</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10013</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>General Counsel</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2012-03-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>255215.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>255215.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2012-03-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>186.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>186.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By minor daughter</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2012-03-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1985.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F3"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1985.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By minor son</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Received in exchange for 165,081 shares of common stock of Vertro, Inc. (&quot;Vertro&quot;) pursuant to an Agreement and Plan of Merger among Vertro, Issuer and Anhinga Merger Subsidiary, Inc. (the &quot;Merger&quot;).  On the effective day of the Merger, the closing price of Issuer's common stock was $0.88 per share, and the closing price of Vertro's common stock was $1.30.</footnote>
        <footnote id="F2">Received in exchange for 120 shares of common stock of Vertro, Inc. (&quot;Vertro&quot;) pursuant to an Agreement and Plan of Merger among Vertro, Issuer and Anhinga Merger Subsidiary, Inc. (the &quot;Merger&quot;).  On the effective day of the Merger, the closing price of Issuer's common stock was $0.88 per share, and the closing price of Vertro's common stock was $1.30.</footnote>
        <footnote id="F3">Received in exchange for 1,284 shares of common stock of Vertro, Inc. (&quot;Vertro&quot;) pursuant to an Agreement and Plan of Merger among Vertro, Issuer and Anhinga Merger Subsidiary, Inc. (the &quot;Merger&quot;).  On the effective day of the Merger, the closing price of Issuer's common stock was $0.88 per share, and the closing price of Vertro's common stock was $1.30.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ John B. Pisaris</signatureName>
        <signatureDate>2012-03-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
