<SEC-DOCUMENT>0000950170-25-021496.txt : 20250214
<SEC-HEADER>0000950170-25-021496.hdr.sgml : 20250214
<ACCEPTANCE-DATETIME>20250214172729
ACCESSION NUMBER:		0000950170-25-021496
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250214
DATE AS OF CHANGE:		20250214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MAIA Biotechnology, Inc.
		CENTRAL INDEX KEY:			0001878313
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-93731
		FILM NUMBER:		25631167

	BUSINESS ADDRESS:	
		STREET 1:		444 WEST LAKE STREET, SUITE 1700
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60606
		BUSINESS PHONE:		312-416-8592

	MAIL ADDRESS:	
		STREET 1:		444 WEST LAKE STREET, SUITE 1700
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60606

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Gryaznov Sergei
		CENTRAL INDEX KEY:			0001913228
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	MAIL ADDRESS:	
		STREET 1:		444 WEST LAKE STREET, SUITE 1700
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60606
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001193125-23-037957</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001913228</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common Stock, $0.0001 par value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2023</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001878313</issuerCik>
        <issuerName>MAIA BIOTECHNOLOGY, INC.</issuerName>
        <issuerCusip>552641102</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <street1 xmlns="http://www.sec.gov/edgar/common">444 West Lake Street</street1>
          <street2 xmlns="http://www.sec.gov/edgar/common">Suite 1700</street2>
          <city xmlns="http://www.sec.gov/edgar/common">Chicago</city>
          <stateOrCountry xmlns="http://www.sec.gov/edgar/common">IL</stateOrCountry>
          <zipCode xmlns="http://www.sec.gov/edgar/common">60606</zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Sergei M. Gryaznov</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>1140115</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>1140115</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1140115</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>4.08</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>(1)	Consists of 1,140,115 shares including: (i) 44,511 shares of common stock and (ii) 1,095,604 shares of common stock issuable upon the exercise of stock options. </comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>MAIA BIOTECHNOLOGY, INC.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>444 West Lake Street, Suite 1700, Chicago, IL 60606</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Sergei M. Gryaznov  </filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>444 West Lake Street, Suite 1700, Chicago, IL 60606  </principalBusinessOfficeOrResidenceAddress>
        <citizenship>United States </citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>1,140,115 shares including: (i) 44,511 shares of common stock and (ii) 1,095,604 shares of common stock issuable upon the exercise of stock options. </amountBeneficiallyOwned>
        <classPercent>4.08%

The foregoing percentage is based on 26,824,681 shares of common stock of the issuer issued and outstanding on February 13, 2025, plus 1,095,604 shares of common stock issuable upon the exercise of stock options exercisable within 60 days of February 13, 2025.
</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>1,140,115 shares including: (i) 44,511 shares of common stock and (ii) 1,095,604 shares of common stock issuable upon the exercise of stock options. </solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>1,140,115 shares including: (i) 44,511 shares of common stock and (ii) 1,095,604 shares of common stock issuable upon the exercise of stock options. </solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>Y</notApplicableFlag>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Sergei M. Gryaznov</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Sergei M. Gryaznov</signature>
        <title>Sergei M. Gryaznov</title>
        <date>02/14/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
