<SEC-DOCUMENT>0001062993-24-021195.txt : 20241226
<SEC-HEADER>0001062993-24-021195.hdr.sgml : 20241226
<ACCEPTANCE-DATETIME>20241226080512
ACCESSION NUMBER:		0001062993-24-021195
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20241226
DATE AS OF CHANGE:		20241226

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Medicus Pharma Ltd.
		CENTRAL INDEX KEY:			0001997296
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			A6
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-279771
		FILM NUMBER:		241576330

	BUSINESS ADDRESS:	
		STREET 1:		100 KING STREET WEST
		STREET 2:		SUITE 3400
		CITY:			TORONTO
		STATE:			A6
		ZIP:			M5X 1A4
		BUSINESS PHONE:		(732) 300-3046

	MAIL ADDRESS:	
		STREET 1:		100 KING STREET WEST
		STREET 2:		SUITE 3400
		CITY:			TORONTO
		STATE:			A6
		ZIP:			M5X 1A4
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>form424b3.htm
<DESCRIPTION>FORM 424B3
<TEXT>
<html>

<head>
    <title>Medicus Pharma Ltd.: Form 424B3 - Filed by newsfilecorp.com</title>
</head>

<body style="font-size:10pt; font-family:'Times New Roman';">
    <hr width="100%" size="3" color="black" noshade="noshade"><a name="page_1"></a>
    <p style="margin-bottom: 0pt; text-align: right; background-color: #ffffff;"><b>Filed Pursuant to Rule 424(b)(3)</b></p>
    <p style="margin-top: 0pt; text-align: right; background-color: #ffffff;"><b>Registration No. 333-279771</b></p>
    <p style="margin-bottom: 0pt; text-align: justify; background-color: #ffffff;"><b>PROSPECTUS SUPPLEMENT NO. 2</b></p>
    <p style="margin-top: 0pt; text-align: justify; background-color: #ffffff;"><b>(to prospectus dated November 13, 2024)</b></p>
    <p style="margin-bottom: 0pt; text-align: center; background-color: #ffffff;"><b>Medicus Pharma Ltd.</b></p>
    <p style="margin-top: 0pt; text-align: center;"><br><b>970,000 Units</b></p>
    <p style="text-align: center;"><b>Consisting of an Aggregate of</b></p>
    <p style="text-align: center;"><b>970,000 Common Shares</b></p>
    <p style="text-align: center;"><b>and</b></p>
    <p style="text-align: center;"><b>970,000 Warrants to Purchase One Common Share</b></p>
    <p style="text-align: center; margin-bottom: 0pt;"><b>970,000 Common Shares Issuable upon the Exercise of the Warrants</b></p>
    <div style="margin-left: 0pt;">
        <table style="width: 40%; border-collapse: collapse; font-size: 10pt; margin-left: auto; margin-right: auto;" cellspacing="0" cellpadding="0">
            <tr>
                <td style="margin-top: 0pt; margin-bottom: 0pt; border-bottom: 0.75pt solid #000000;">
                    <p>&#160;</p>
                </td>
            </tr>
        </table>
    </div>
    <p style="text-align: justify; background-color: #ffffff;">This prospectus supplement amends and supplements the prospectus dated November 13, 2024, as supplemented or amended from time to time (the "Prospectus"), which forms a part of our Registration Statement on Form F-1 (Registration Statement No. 333-279771). This prospectus supplement is being filed to update and supplement the information included or incorporated by reference in the Prospectus with the information contained in our Report on Form 6-K, furnished to the Securities and Exchange Commission on December 26, 2024 (the "Form 6-K"). Accordingly, we have attached the Form 6-K to this prospectus supplement.</p>
    <p style="text-align: justify; background-color: #ffffff;">This prospectus supplement updates and supplements the information in the Prospectus and is not complete without, and may not be delivered or utilized except in combination with, the Prospectus, including any amendments or supplements thereto. This prospectus supplement should be read in conjunction with the Prospectus and if there is any inconsistency between the information in the Prospectus and this prospectus supplement, you should rely on the information in this prospectus supplement.</p>
    <p style="text-align: justify; background-color: #ffffff;">Our common shares and warrants are listed on The Nasdaq Capital Market ("Nasdaq") under the symbols "MDCX" and "MDCXW," respectively. Our common shares are listed in Canada on the TSX Venture Exchange (the "TSXV") under the symbol "MDCX." On December 24, 2024, the last reported sales prices of the common shares on Nasdaq and the TSXV were $2.64 and C$3.95, respectively, and the last reported sales prices of the warrants on Nasdaq was $0.88.</p>
    <p style="text-align: justify; background-color: #ffffff;"><b>We are an "emerging growth company" under applicable Securities and Exchange Commission rules and are eligible for reduced public company disclosure requirements.</b></p>
    <p style="text-align: justify; background-color: #ffffff;"><b>Investing in our securities involves a high degree of risk. You should review carefully the risks and uncertainties described under the heading "Risk Factors" beginning on page 8 of the Prospectus, and under similar headings in any amendment or supplements to the Prospectus.</b></p>
    <p style="text-align: justify; background-color: #ffffff;"><b>None of the Securities and Exchange Commission, any state securities commission or the securities commission of any Canadian province or territory has approved or disapproved of the securities offered by this prospectus supplement or the Prospectus or determined if the Prospectus or this prospectus supplement is truthful or complete. Any representation to the contrary is a criminal offense.</b></p>
    <p style="text-align: center; background-color: #ffffff;"><b>The date of this prospectus supplement is December 26, 2024.</b></p>
    <hr style="page-break-after: always;" width="100%" size="5" color="black" noshade="noshade"><a name="page_2"></a>
    <p style="margin-bottom: 0pt; text-align: center;"><font style="font-size: 18pt;"><b>UNITED STATES</b></font></p>
    <p style="margin-top: 0pt; margin-bottom: 0pt; text-align: center;"><font style="font-size: 18pt;"><b>SECURITIES AND EXCHANGE COMMISSION</b></font></p>
    <p style="margin-top: 0pt; text-align: center;">Washington, D.C. 20549</p>
    <p style="margin-top: 0pt; text-align: center;"><font style="font-size: 18pt;"><b>Form 6-K</b></font></p>
    <p style="margin-bottom: 0pt; text-align: center;"><b>REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE</b></p>
    <p style="margin-top: 0pt; text-align: center;"><b>SECURITIES EXCHANGE ACT OF 1934</b></p>
    <p style="margin-bottom: 0pt; text-align: center;">For the month of <u><b>December 2024</b></u>.</p>
    <p style="margin-top: 0pt; text-align: center;">Commission File Number <u><b>001-42408</b></u></p>
    <p style="text-align: center;"><font style="font-size: 18pt;"><b><u>MEDICUS PHARMA LTD.</u></b></font><br>(Translation of registrant's name into English)</p>
    <p style="margin-bottom: 0pt; text-align: center;"><b>Suite 3400, 100 King St W</b></p>
    <p style="margin-top: 0pt; margin-bottom: 0pt; text-align: center;"><u><b>Toronto, Ontario, Canada, M5X 1A4</b></u></p>
    <p style="margin-top: 0pt; text-align: center;">(Address of principal executive office)</p>
    <p style="text-align: justify;">Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.</p>
    <p style="text-align: center;">Form 20-F &#9746;<font style="width: 17.83pt; display: inline-block;">&#160;</font>Form 40-F &#9744;</p>
    <hr style="page-break-after: always;" width="100%" size="5" color="black" noshade="noshade"><a name="page_3"></a>
    <p style="text-align: center;"><b>INDEX TO EXHIBITS</b></p>
    <table style="width: 100%; border-collapse: collapse; font-size: 10pt;" cellspacing="0" cellpadding="0">
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%; border-bottom: 0.75pt solid #000000; white-space: nowrap;"><b>Exhibit</b></td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 2%; white-space: nowrap;">&#160;</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 93%; border-bottom: 0.75pt solid #000000; white-space: nowrap;"><b>Description</b></td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%; background-color: #eeeeee;">99.1</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 2%; background-color: #eeeeee;">&#160;</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 93%; background-color: #eeeeee;">Notice of Change of Auditor</td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%;">99.2</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 2%;">&#160;</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 93%;">Letter of Former Auditor</td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%; background-color: #eeeeee;">99.3</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 2%; background-color: #eeeeee;">&#160;</td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 93%; background-color: #eeeeee;">Letter of Successor Auditor</td>
        </tr>
    </table>
    <br>
    <hr style="page-break-after: always;" width="100%" size="5" color="black" noshade="noshade"><a name="page_4"></a>
    <p style="text-align: center;"><b>SIGNATURES</b></p>
    <p style="text-indent: 36pt; text-align: justify;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.</p>
    <table style="width: 100%; border-collapse: collapse; font-size: 10pt;" cellspacing="0" cellpadding="0">
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 50%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 45%;">
                <p><b>Medicus Pharma Ltd.</b></p>
            </td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 50%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 45%;">
                <p>&#160;</p>
            </td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 50%;">
                <p>Date: December 26, 2024</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%;">
                <p>By:</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; border-bottom: 0.75pt solid #000000; width: 45%;">
                <p><i>/s/ Raza Bokhari</i></p>
            </td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 50%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 45%;">
                <p>Name: Dr. Raza Bokhari</p>
            </td>
        </tr>
        <tr>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 50%;">
                <p>&#160;</p>
            </td>
            <td style="margin-top: 0pt; margin-bottom: 0pt; width: 5%;">
                <p>&#160;</p>
            </td>
            <td style="vertical-align: middle; width: 45%;">
                <p style="margin-bottom: 0pt; margin-top: 0pt;">Title:<font style="display: inline-block; width: 4pt;">&#160;</font>Executive Chairman and Chief</p>
                <p style="margin-top: 0pt; margin-bottom: 0pt;"><font style="display: inline-block; width: 25.5pt;">&#160;</font>Executive Officer</p>
            </td>
        </tr>
    </table>
    <br>
    <hr style="page-break-after: always;" width="100%" size="5" color="black" noshade="noshade"><a name="page_5"></a>
    <p style="text-align: right;"><b><font style="color: #000000; font-family: 'Times New Roman'; font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; text-align: right; text-indent: 0px; text-transform: none; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><b>Exhibit 99.1</b></font></b></p>
    <p style="text-align: center;"><b>NOTICE OF CHANGE OF AUDITOR</b></p>
    <table style="width: 100%; border-collapse: collapse; font-size: 10pt;" border="0" cellspacing="0" cellpadding="0">
        <tr>
            <td style="width: 5%; vertical-align: top;"><b>TO:</b></td>
            <td style="vertical-align: top;">EisnerAmper LLP</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">MNP LLP</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">&#160;</td>
        </tr>
        <tr>
            <td style="width: 5%; white-space: nowrap; padding-right: 15pt; vertical-align: top;"><b>AND TO:</b></td>
            <td style="vertical-align: top;">Ontario Securities Commission<br>Alberta Securities Commission<br>British Columbia Securities Commission<br>The Manitoba Securities Commission</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">Financial and Consumer Affairs Authority of Saskatchewan<br>Financial and Consumer Services Commission (New Brunswick)</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">Nova Scotia Securities Commission</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">Government of Newfoundland and Labrador, Office of the Superintendent<br>Prince Edward Island Securities Office</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">Autorit&#233; des march&#233;s financiers</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">Government of Nunavut Office of the Superintendent of Securities</td>
        </tr>
        <tr>
            <td style="width: 5%; vertical-align: top;">&#160;</td>
            <td style="vertical-align: top;">Government of the Northwest Territories, Office of the Superintendent of Securities<br>Office of the Superintendent of Securities, Government of Yukon</td>
        </tr>
    </table>
    <p style="text-align: justify;">Medicus Pharma Ltd. (the "<b>Corporation</b>") hereby provides notice pursuant to Section 4.11 of National Instrument 51-102 of the resignation of MNP LLP (the "<b>Former Auditor</b>") as the auditor of the Corporation and the appointment EisnerAmper LLP (the "<b>Successor Auditor</b>") in its place.</p>
    <p style="text-align: justify;">The Corporation confirms that:</p>
    <p style="text-align: justify; text-indent: -27pt; margin-left: 36pt;">1.<font style="width: 19.5pt; display: inline-block;">&#160;</font>On its own initiative, the Former Auditor tendered its resignation as auditor of the Corporation effective December 19, 2024.</p>
    <p style="text-align: justify; text-indent: -27pt; margin-left: 36pt;">2.<font style="width: 19.5pt; display: inline-block;">&#160;</font>The resignation of the Former Auditor has been approved by the audit committee and the board of directors of the Corporation.</p>
    <p style="text-align: justify; text-indent: -27pt; margin-left: 36pt;">3.<font style="width: 19.5pt; display: inline-block;">&#160;</font>The appointment of the Successor Auditor has been approved by the audit committee and the board of directors of the Corporation, effective December 19, 2024.</p>
    <p style="text-align: justify; text-indent: -27pt; margin-left: 36pt;">4.<font style="width: 19.5pt; display: inline-block;">&#160;</font>There are no reservations or modified opinions in the Former Auditor's reports for the Corporation's financial statements for the "relevant period" (as defined in NI 51-102).</p>
    <p style="text-align: justify; margin-left: 9pt;">5.<font style="width: 19.5pt; display: inline-block;">&#160;</font>There have been no "reportable events" as defined in Section 4.11 of National Instrument 51-102.</p>
    <p style="text-align: justify; margin-left: 5.25pt;"><b>DATED </b>as of the 23<sup>rd </sup>day of December, 2024.</p>
    <table style="width: 100%; font-size: 10pt; border-collapse: collapse;" border="0" cellspacing="0" cellpadding="0">
        <tr>
            <td style="width: 50%;">&#160;</td>
            <td colspan="2"><b>MEDICUS PHARMA LTD.</b></td>
        </tr>
        <tr>
            <td>&#160;</td>
            <td style="width: 5%;">&#160;</td>
            <td>&#160;</td>
        </tr>
        <tr>
            <td>&#160;</td>
            <td>Per:</td>
            <td style="border-bottom: 0.75pt solid #000000;"><i>(signed) "Raza Bokhari"</i></td>
        </tr>
        <tr>
            <td>&#160;</td>
            <td>&#160;</td>
            <td>Raza Bokhari</td>
        </tr>
        <tr>
            <td>&#160;</td>
            <td>&#160;</td>
            <td>Chief Executive Officer</td>
        </tr>
    </table>
    <br>
    <hr style="page-break-after: always;" width="100%" size="5" color="black" noshade="noshade"><a name="page_6"></a>
    <p style="text-align: right;"><font style="color: #000000; font-family: 'Times New Roman'; font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; text-align: right; text-indent: 0px; text-transform: none; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><b>Exhibit 99.2</b></font></p>
    <p style="text-align: right;"><img src="form424b3xu001.jpg"></p>
    <p style="text-align: justify;">December 23, 2024</p>
    <p style="text-align: justify;">&#160;</p>
    <p style="text-align: justify; margin-bottom: 0pt;">Ontario Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">British Columbia Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Alberta Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Financial and Consumer Affairs Authority of Saskatchewan</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Manitoba Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">New Brunswick Financial and Consumer Services Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Nova Scotia Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Prince Edward Island Office of the Superintendent of Securities</p>
    <p style="text-align: justify; margin-top: 0pt;">Securities NL, Government of Newfoundland and Labrador</p>
    <p style="text-align: justify;">Dear Sirs/Mesdames:</p>
    <p style="text-align: justify;"><b>Re: Medicus Pharma Ltd. - Change of Auditor</b></p>
    <p style="text-align: justify;">Pursuant to National Instrument 51-102 - <i>Continuous Disclosure Obligations, </i>we have reviewed the information contained in the Notice of Change of Auditor of Medicus Pharma Limited dated December 19, 2024 (the <b>"Notice</b>") and, based on our knowledge of such information at this time:</p>
    <p style="text-align: justify; text-indent: -18pt; margin-left: 36pt;">1.<font style="width: 10.5pt; display: inline-block;">&#160;</font>We agree with paragraphs 1, 4 and 5 of the Notice.</p>
    <p style="text-align: justify; text-indent: -18pt; margin-left: 36pt;">2.<font style="width: 10.5pt; display: inline-block;">&#160;</font>With respect to paragraph 2 and 3 of the Notice, we have no basis on which to agree or disagree.</p>
    <p style="text-align: justify;">Yours very truly,</p>
    <p style="text-align: justify;"><img src="form424b3xu002.jpg"></p>
    <p style="text-align: justify; margin-bottom: 0pt;">Chartered Professional Accountants</p>
    <p style="text-align: justify; margin-top: 0pt;">Mississauga, Ontario</p>
    <p style="text-align: justify; margin-top: 0pt;">&#160;</p>
    <br>
    <table style="width: 100%; border-collapse: collapse; font-size: 10pt;" border="0" cellspacing="0" cellpadding="0">
        <tr>
            <td style="width: 50%; vertical-align: bottom;" rowspan="2"><img src="form424b3xu003.jpg"></td>
            <td style="width: 50%; text-align: right; vertical-align: bottom;"><img src="form424b3xu006.jpg">&#160;</td>
        </tr>
        <tr>
            <td style="width: 50%; text-align: right; vertical-align: bottom;"><font style="color: #005244;">SUITE 800, 1600 CARLING AVENUE, OTTAWA ON, K1Z 1G3<br>T: 613.691.4200 F: 613.726.9009 <b>MNP.ca</b><br></font></td>
        </tr>
    </table>
    <br>
    <hr style="page-break-after: always;" width="100%" size="5" color="black" noshade="noshade"><a name="page_7"></a>
    <p style="text-align: right;"><font style="color: #000000; font-family: 'Times New Roman'; font-size: 13.3333px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; text-align: right; text-indent: 0px; text-transform: none; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><b>Exhibit 99.3</b></font></p>
    <table style="width: 100%; border-collapse: collapse; font-size: 10pt;" border="0" cellspacing="0" cellpadding="0">
        <tr>
            <td style="width: 50%; vertical-align: top;"><img src="form424b3xu004.jpg"></td>
            <td style="width: 50%; text-align: right; vertical-align: top;"><b>EisnerAmper LLP</b><br>One Logan Square<br>130 North 18th Street, Suite 3000<br>Philadelphia, PA 19103<br><b>T </b>215.881.8800<br><b>F </b>215.881.8801<br><font style="color: #bd9b60;">www.eisneramper.com</font></td>
        </tr>
    </table>
    <p style="text-align: right; margin-top: 0pt;">&#160;</p>
    <p style="text-align: justify;">December 23, 2024</p>
    <p style="text-align: justify; margin-bottom: 0pt;">British Columbia Securities Commission<br>Alberta Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Financial and Consumer Affairs Authority of Saskatchewan<br>The Manitoba Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Ontario Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Financial and Consumer Services Commission - New Brunswick<br>Nova Scotia Securities Commission</p>
    <p style="text-align: justify; margin-top: 0pt; margin-bottom: 0pt;">Office of the Superintendent of Securities - Prince Edward Island</p>
    <p style="text-align: justify; margin-top: 0pt;">Office of the Superintendent of Securities - Service Newfoundland and Labrador</p>
    <table style="width: 100%; font-size: 10pt; border-collapse: collapse;" cellspacing="0" cellpadding="0">
        <tr>
            <td style="width: 3%; vertical-align: bottom; padding-right: 15pt;">
                <p style="text-align: left;">Re:</p>
            </td>
            <td style="vertical-align: bottom;">
                <p style="text-align: left;">Medicus Pharma Limited</p>
            </td>
        </tr>
        <tr>
            <td style="width: 3%; vertical-align: bottom;">
                <p style="text-align: left;">&#160;</p>
            </td>
            <td style="vertical-align: bottom;">
                <p style="text-align: left; margin-left: 0.75pt;">Change of Auditor Notice dated December 23, 2024</p>
            </td>
        </tr>
        <tr>
            <td style="border-bottom: 1px solid #000000; width: 3%; vertical-align: bottom;">
                <p style="text-align: left;">&#160;</p>
            </td>
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                <p style="text-align: left;">&#160;</p>
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    <p style="text-align: justify;">Pursuant to National Instrument 51-102 (Part 4.11), we have read the above-noted Change of Auditor Notice and confirm our agreement with the information contained in the Notice pertaining to our firm.</p>
    <p style="text-align: justify;">Yours sincerely,</p>
    <p style="text-align: justify;"><img src="form424b3xu005.jpg"></p>
    <p style="text-align: justify; margin-bottom: 0pt;">EisnerAmper LLP</p>
    <p style="text-align: justify; margin-top: 0pt;">Philadelphia, Pennsylvania</p>
    <p style="text-align: justify; margin-top: 0pt;">&#160;</p>
    <p style="text-align: justify;"><font style="color: #808080;">"EisnerAmper" is the brand name under which EisnerAmper LLP and Eisner Advisory Group LLC and its subsidiary entities provide professional services. EisnerAmper LLP and Eisner Advisory Group LLC are independently owned firms that practice in an alternative practice structure in accordance with the AICPA Code of Professional Conduct and applicable law, regulations and professional standards. EisnerAmper LLP is a licensed CPA firm that provides attest services, and Eisner Advisory Group LLC and its subsidiary entities provide tax and business consulting services. Eisner Advisory Group LLC and its subsidiary entities are not licensed CPA firms.</font></p>
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