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Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2024

Stock-Based Compensation

Schedule of stock option activity

​

​	​	​	​	​	​	​
​	​	​	​	​		​
​	​	Number of	​	Weighted average		​
​		shares		price per share
​	​	​	​	​	​	​
Outstanding as of January 1, 2024		4,976	​	$	18.52	​
Granted	​	95	​	$	1.53	​
Forfeited	​	(120)	​	$	18.38	​
Cancelled	​	(119)	​	$	21.44	​
Exercised	​	—	​	$	—	​
Outstanding as of June 30, 2024	​	4,832	​	$	18.12	​
​	​	​	​	​	​	​
Options vested and exercisable as of June 30, 2024		3,892	​	$	18.10	​

Schedule of stock-based compensation charges

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Three months ended June 30,

​

Six months ended June 30,

​

​

2024

​

2023

​

2024

​

2023

​

​

​

​

​

​

​

​

​

​

​

​

​

Research and development

$

282

​

$

1,898

​

$

1,563

​

$

3,195

Selling, general and administrative

​

775

​

​

4,226

​

2,927

​

​

7,806

Total

​

$

1,057

​

$

6,124

​

$

4,490

​

$

11,001

BTI RSU

Stock-Based Compensation

Schedule of activity relating to RSUs

​

​	​	​
​	​	​
​	​	Number of
​		shares
​	​	​
Outstanding as of January 1, 2024		185
Granted	​	5
Cancelled	​	(6)
Vested	​	(55)
Outstanding as of June 30, 2024	​	129

BTI PSU

Stock-Based Compensation

Schedule of activity relating to PSUs

​

​	​	​
​	​	Number of
​		shares
​	​	​
Outstanding as of January 1, 2024		527
Granted	​	—
Cancelled	​	(98)
Outstanding as of June 30, 2024	​	429

OnkosXcel PSU

Stock-Based Compensation

Schedule of activity relating to PSUs

​

​	​	​	​	​	​
​	​	​	​	​	​
​	​	​	​	Weighted average
​	​	Number of	​	price per unit
​		units	​	(in whole dollars)
​	​	​	​	​	​
Outstanding as of January 1, 2024		1,240	​	$	5,626
Granted	​	—	​	$	—
Cancelled	​	(79)	​	$	5,506
Forfeited	​	—	​	$	—
Outstanding as of June 30, 2024	​	1,161	​	​	​
​	​	​	​	​	​
Vested units as of June 30, 2024	​	847	​	$	5,550

Schedule of Valuation Assumptions

​

​	​	​	​	​
​	​	​	​	​
​	​	2023 grant profit share unit valuation inputs		​
​	​	​	​	​
Expected volatility	​	97.4	%	​
Risk-free rate of interest	​	3.6	%	​
Expected dividend yield	​	—	%	​
Expected term	​	5.8	years	​

OnkosXcel RSUs

Stock-Based Compensation

Schedule of activity relating to RSUs

​

​	​	​
​	​	​
​	​	Number of
​		units
​	​	​
Outstanding as of January 1, 2024		225
Granted	​	—
Cancelled	​	(8)
Outstanding as of June 30, 2024	​	217

Employee Stock Option

Stock-Based Compensation

Schedule of Valuation Assumptions

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Six months ended

​

Six months ended

​

​

June 30, 2024

​

June 30, 2023

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Expected term

​

​

5.5

years

-

6.1

years

​

5.5

years

-

6.1

years

Expected stock price volatility

​

​

108.0

%

-

112

%

​

96.6

%

-

97.9

%

Risk-free rate of interest

​

​

4.0

%

-

4.5

%

​

3.5

%

-

4.2

%

Expected dividend yield

​

​

0.0

%

-

0.0

%

​

0.0

%

-

0.0

%

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