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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2024
Stock-Based Compensation |
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Number of | ​ | Weighted average | ​
​ |  | shares |  | price per share |
​ | ​ | ​ | ​ | ​ | ​ | ​
Outstanding as of January 1, 2024 |  | 4,976 | ​ | $ | 18.52 | ​
Granted | ​ | 632 | ​ | $ | 1.25 | ​
Forfeited | ​ | (141) | ​ | $ | 17.77 | ​
Cancelled | ​ | (238) | ​ | $ | 21.48 | ​
Exercised | ​ | — | ​ | $ | — | ​
Outstanding as of September 30, 2024 | ​ | 5,229 | ​ | $ | 16.32 | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
Options vested and exercisable as of September 30, 2024 |  | 3,895 | ​ | $ | 18.16 | ​
Schedule of stock-based compensation charges | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three months ended September 30, | ​ | Nine months ended September 30,
​ | ​ | 2024 | ​ | 2023 | ​ | 2024 | ​ | 2023
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Research and development |  | $ | 884 | ​ | $ | 1,645 | ​ | $ | 2,446 | ​ | $ | 4,840
Selling, general and administrative | ​ |  | 981 | ​ | ​ | 2,369 | ​ |  | 3,909 | ​ | ​ | 10,175
Total | ​ | $ | 1,865 | ​ | $ | 4,014 | ​ | $ | 6,355 | ​ | $ | 15,015
BTI RSU |
Stock-Based Compensation |
Schedule of activity relating to RSUs | ​
​ | ​ | ​
​ | ​ | ​
​ | ​ | Number of
​ |  | shares
​ | ​ | ​
Outstanding as of January 1, 2024 |  | 185
Granted | ​ | 25
Cancelled | ​ | (6)
Vested | ​ | (69)
Outstanding as of September 30, 2024 | ​ | 135
BTI PSU |
Stock-Based Compensation |
Schedule of activity relating to PSUs | ​
​ | ​ | ​
​ | ​ | Number of
​ |  | shares
​ | ​ | ​
Outstanding as of January 1, 2024 |  | 527
Granted | ​ | 1,388
Cancelled | ​ | (125)
Outstanding as of September 30, 2024 | ​ | 1,790
OnkosXcel PSU |
Stock-Based Compensation |
Schedule of activity relating to PSUs | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted average
​ | ​ | Number of | ​ | price per unit
​ |  | units | ​ | (in whole dollars)
​ | ​ | ​ | ​ | ​ | ​
Outstanding as of January 1, 2024 |  | 1,240 | ​ | $ | 5,626
Granted | ​ | 15 | ​ | $ | 10,176
Cancelled | ​ | (79) | ​ | $ | 5,506
Forfeited | ​ | — | ​ | $ | —
Outstanding as of September 30, 2024 | ​ | 1,176 | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​
Vested units as of September 30, 2024 | ​ | 906 | ​ | $ | 5,557
Schedule of Valuation Assumptions | ​
​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​
​ | ​ | 2024 grant profit share unit valuation inputs | ​
​ | ​ | ​ | ​ | ​
Expected volatility | ​ | 97.4 | % | ​
Risk-free rate of interest | ​ | 3.6 | % | ​
Expected dividend yield | ​ | — | % | ​
Expected term | ​ | 5.8 | years | ​
OnkosXcel RSUs |
Stock-Based Compensation |
Schedule of activity relating to RSUs | ​
​ | ​ | ​
​ | ​ | ​
​ | ​ | Number of
​ |  | units
​ | ​ | ​
Outstanding as of January 1, 2024 |  | 225
Granted | ​ | —
Vested | ​ | (35)
Cancelled | ​ | (8)
Outstanding as of September 30, 2024 | ​ | 182
​ | ​ | ​
Employee Stock Option |
Stock-Based Compensation |
Schedule of Valuation Assumptions | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​
​ | ​ | Nine months ended | ​ | Nine months ended
​ |  | ​ | September 30, 2024 | ​ | September 30, 2023
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Expected term | ​ | ​ | 5.5 | years | - | 6.1 | years | ​ | 5.5 | years | - | 6.1 | years
Expected stock price volatility | ​ | ​ | 108.0 | % | - | 112.5 | % | ​ | 96.6 | % | - | 109.2 | %
Risk-free rate of interest | ​ | ​ | 4.0 | % | - | 4.5 | % | ​ | 3.5 | % | - | 4.4 | %
Expected dividend yield | ​ | ​ | 0.0 | % | - | 0.0 | % | ​ | 0.0 | % | - | 0.0 | %

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- Definition Tabular disclosure of number, weighted-average exercise price or conversion ratio, aggregate intrinsic value, and weighted-average remaining contractual term for outstanding performance-based awards that are fully vested and expected to vest. Includes, but is not limited to, unvested awards for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (e)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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