<SEC-DOCUMENT>0001104659-24-044862.txt : 20240408
<SEC-HEADER>0001104659-24-044862.hdr.sgml : 20240408
<ACCEPTANCE-DATETIME>20240408193258
ACCESSION NUMBER:		0001104659-24-044862
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20240314
FILED AS OF DATE:		20240408
DATE AS OF CHANGE:		20240408

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			O'Neill Vincent
		CENTRAL INDEX KEY:			0001672718
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38410
		FILM NUMBER:		24830835

	MAIL ADDRESS:	
		STREET 1:		2150 WOODWARD ST., SUITE 100
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78744

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BioXcel Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001720893
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				821386754
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		555 LONG WHARF DRIVE
		CITY:			NEW HAVEN
		STATE:			CT
		ZIP:			06511
		BUSINESS PHONE:		203-643-8060

	MAIL ADDRESS:	
		STREET 1:		555 LONG WHARF DRIVE
		CITY:			NEW HAVEN
		STATE:			CT
		ZIP:			06511
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
<FILENAME>tm2411220-6_4seq1.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
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    <periodOfReport>2024-03-14</periodOfReport>

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    <issuer>
        <issuerCik>0001720893</issuerCik>
        <issuerName>BioXcel Therapeutics, Inc.</issuerName>
        <issuerTradingSymbol>BTAI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001672718</rptOwnerCik>
            <rptOwnerName>O'Neill Vincent</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O BIOXCEL THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>555 LONG WHARF DRIVE, 12TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW HAVEN</rptOwnerCity>
            <rptOwnerState>CT</rptOwnerState>
            <rptOwnerZipCode>06511</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>1</aff10b5One>

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                </transactionShares>
                <transactionPricePerShare>
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        </nonDerivativeTransaction>
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    <derivativeTable>
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            </securityTitle>
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                </transactionShares>
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                </transactionPricePerShare>
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            <underlyingSecurity>
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                </underlyingSecurityShares>
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            <transactionAmounts>
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                    <value>2250</value>
                </transactionShares>
                <transactionPricePerShare>
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                </transactionPricePerShare>
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                <underlyingSecurityShares>
                    <value>2250</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
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                <sharesOwnedFollowingTransaction>
                    <value>6750</value>
                </sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
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        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Each Restricted Stock Unit (&quot;RSU&quot;) represents a contingent right to receive one share of the Issuer's Common Stock.</footnote>
        <footnote id="F2">The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 15, 2023.</footnote>
        <footnote id="F3">On March 14, 2022, the Reporting Person was granted 8,337 RSUs, vesting as to 25% of the total number of RSUs on the first anniversary of March 14, 2022 and as to 6.25% of the total number of RSUs at the end of each successive three-month period thereafter, subject to the Reporting Person's continuous employment with the Issuer through the relevant vesting dates.</footnote>
        <footnote id="F4">On March 15, 2023, the Reporting Person was granted 9,000 RSUs, vesting as to 25% of the total number of RSUs on the first anniversary of March 15, 2023 and as to 6.25% of the total number of RSUs at the end of each successive three-month period thereafter, subject to the Reporting Person's continuous employment with the Issuer through the relevant vesting dates.</footnote>
    </footnotes>

    <remarks>Executive Vice President, Chief of Product Development and Medical Officer</remarks>

    <ownerSignature>
        <signatureName>/s/ Richard Steinhart, as Attorney in Fact for Vincent O'Neill</signatureName>
        <signatureDate>2024-04-08</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</SEC-DOCUMENT>
