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v3.25.1

Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2025
Stock-Based Compensation |
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Number of | ​ | Weighted average | ​
​ |  | shares |  | price per share |
​ | ​ | ​ | ​ | ​ | ​ | ​
Outstanding as of January 1, 2025 |  | 311 | ​ | $ | 265.36 | ​
Granted | ​ | 75 | ​ | $ | 7.54 | ​
Forfeited | ​ | (5) | ​ | $ | 124.94 | ​
Cancelled | ​ | (14) | ​ | $ | 384.60 | ​
Exercised | ​ | — | ​ | $ | — | ​
Outstanding as of March 31, 2025 | ​ | 367 | ​ | $ | 210.27 | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
Options vested and exercisable as of March 31, 2025 |  | 259 | ​ | $ | 268.46 | ​
Schedule of stock-based compensation charges | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three months ended March 31,
​ | ​ | 2025 | ​ | 2024
​ | ​ | ​ | ​ | ​ | ​ | ​
Research and development | ​ | $ | (514) | ​ | $ | 1,281
Selling, general and administrative | ​ |  | 694 | ​ | ​ | 2,152
Total | ​ | $ | 180 | ​ | $ | 3,433
BTI RSU |
Stock-Based Compensation |
Schedule of activity relating to RSUs | ​
​ | ​ | ​
​ | ​ | ​
​ | ​ | Number of
​ |  | shares
​ | ​ | ​
Outstanding as of January 1, 2025 |  | 27
Granted | ​ | 3
Cancelled | ​ | (1)
Vested | ​ | (9)
Outstanding as of March 31, 2025 | ​ | 20
BTI PSU |
Stock-Based Compensation |
Schedule of activity relating to PSUs | ​
​ | ​ | ​
​ | ​ | Number of
​ |  | shares
​ | ​ | ​
Outstanding as of January 1, 2025 |  | 70
Granted | ​ | —
Cancelled | ​ | (10)
Exercised | ​ | —
Outstanding as of March 31, 2025 | ​ | 60
OnkosXcel PSU |
Stock-Based Compensation |
Schedule of activity relating to PSUs | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted average
​ | ​ | Number of | ​ | price per unit
​ |  | units | ​ | (in whole dollars)
​ | ​ | ​ | ​ | ​ | ​
Outstanding as of January 1, 2025 |  | 1,166 | ​ | $ | 5,686
Granted | ​ | — | ​ | $ | —
Cancelled | ​ | (84) | ​ | $ | 6,006
Forfeited | ​ | — | ​ | $ | —
Outstanding as of March 31, 2025 | ​ | 1,082 | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​
Vested units as of March 31, 2025 | ​ | 976 | ​ | $ | 5,533
Schedule of Valuation Assumptions | ​
​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​
​ | ​ | 2024 grant profit share unit valuation inputs | ​
​ | ​ | ​ | ​ | ​
Expected volatility | ​ | 97.4 | % | ​
Risk-free rate of interest | ​ | 3.6 | % | ​
Expected dividend yield | ​ | — | % | ​
Expected term | ​ | 5.8 | years | ​
OnkosXcel RSUs |
Stock-Based Compensation |
Schedule of activity relating to RSUs | ​
​ | ​ | ​
​ | ​ | ​
​ | ​ | Number of
​ |  | units
​ | ​ | ​
Outstanding as of January 1, 2025 |  | 176
Granted | ​ | —
Vested | ​ | (2)
Cancelled | ​ | (34)
Outstanding as of March 31, 2025 | ​ | 140
​ | ​ | ​
Employee Stock Option |
Stock-Based Compensation |
Schedule of Valuation Assumptions | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​
​ | ​ | Three months ended | ​ | Three months ended
​ |  | ​ | March 31, 2025 | ​ | March 31, 2024
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Expected term | ​ | ​ | ​ | ​ | 5.3 | years | ​ | ​ | ​ | ​ | 6.1 | years | ​
Expected stock price volatility | ​ | ​ | ​ | ​ | 112.0 | % | ​ | ​ | ​ | ​ | 108.4 | % | ​
Risk-free rate of interest | ​ | ​ | ​ | ​ | 4.5 | % | ​ | ​ | ​ | ​ | 4.0 | % | ​
Expected dividend yield | ​ | ​ | ​ | ​ | 0.0 | % | ​ | ​ | ​ | ​ | 0.0 | % | ​

X
- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of number, weighted-average exercise price or conversion ratio, aggregate intrinsic value, and weighted-average remaining contractual term for outstanding performance-based awards that are fully vested and expected to vest. Includes, but is not limited to, unvested awards for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (e)(1) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Line items represent financial concepts included in a table. 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