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Consolidated Statements of Shareholders' Equity - USD ($)
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Balance at Dec. 31, 2012 $ 14,172,675 $ 2,265 $ 101,846,779 $ (87,676,369)
Balance, shares at Dec. 31, 2012   22,646,782    
Exercise of options and warrants 822,969 $ 18 822,951
Exercise of options and warrants, shares   179,983    
Share-based compensation 2,914,904 $ 28 $ 2,914,876
Share-based compensation, shares   282,900    
Net Loss (6,040,611) $ (6,040,611)
Balance at Dec. 31, 2013 11,869,937 $ 2,311 $ 105,584,606 $ (93,716,980)
Balance, shares at Dec. 31, 2013   23,109,665    
Issuance of Common Stock 3,278,250 $ 75 3,278,175  
Issuance of Common Stock, shares   750,000    
Exercise of options and warrants $ 304,788 $ 6 304,782
Exercise of options and warrants, shares 64,800 64,800    
Share-based compensation $ 1,042,917 $ 1,042,917
Share-based compensation, shares      
Net Loss (4,413,722) $ (4,413,722)
Balance at Dec. 31, 2014 12,082,170 $ 2,392 $ 110,210,480 $ (98,130,702)
Balance, shares at Dec. 31, 2014   23,924,465    
Exercise of options and warrants $ 548,475 $ 12 548,463
Exercise of options and warrants, shares 119,381 119,381    
Share-based compensation $ 725,016 $ 725,016
Share-based compensation, shares      
Net Loss (4,279,856) $ (4,279,856)
Balance at Dec. 31, 2015 $ 9,075,805 $ 2,404 $ 111,483,959 $ (102,410,558)
Balance, shares at Dec. 31, 2015   24,043,846