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Consolidated Statements of Cash Flows - USD ($)
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Cash flows from operating activities:      
Net loss $ (4,279,856) $ (4,413,722) $ (6,040,611)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 140,170 31,824 45,212
Stock based compensation 725,016 1,042,917 2,914,904
Bad debts 324,286 131,250 81,198
Change in assets and liabilities:      
Royalty receivables (463,743) (439,306) (260,042)
Prepaid expenses and other current assets (12,213) 2,866 94,544
Accounts payable and accrued expenses $ (14,472) 345,356 $ (80,064)
Deferred revenue (25,000)
Net cash used in operating activities $ (3,580,812) (3,323,815) $ (3,244,859)
Cash flows from investing activities:      
Purchases of fixed assets $ (316,185) (627,660) (50,536)
Purchase of investments (3,005,079) $ (24,009)
Proceeds from sale of investment $ 1,491,295 5,076,930
Net cash provided by (used in) investing activities 1,175,110 1,444,191 $ (74,545)
Cash flows from financing activities:      
Net proceeds from issuances of common stock and exercise of options and warrants 548,475 3,583,038 795,294
Net cash provided by financing activities 548,475 3,583,038 795,294
Net (decrease) increase in cash and cash equivalents (1,857,227) 1,703,414 (2,524,110)
Cash and cash equivalents at beginning of year 7,569,537 5,866,123 8,390,233
Cash and cash equivalents at end of year $ 5,712,310 $ 7,569,537 $ 5,866,123