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Consolidated Statements of Cash Flows - USD ($)
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Cash flows from operating activities:      
Net loss $ (4,238,410) $ (4,279,856) $ (4,413,722)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 188,501 140,170 31,824
Stock based compensation 67,531 725,016 1,042,917
Loss on sale of fixed asset 1,775
Bad debts 480,563 324,286 131,250
Change in assets and liabilities:      
Royalty receivables (283,034) (463,743) (439,306)
Prepaid expenses and other current assets (123,427) (12,213) 2,866
Accounts payable and accrued expenses (98,942) (14,472) 345,356
Deferred revenue (25,000)
Net cash used in operating activities (4,005,443) (3,580,812) (3,323,815)
Cash flows from investing activities:      
Purchases of fixed assets (11,715) (316,185) (627,660)
Purchase of investments (3,005,079)
Proceeds from sale of fixed asset 6,000
Proceeds from sale of investment (9,549) 1,491,295 5,076,930
Net cash used in (provided by) investing activities (15,264) 1,175,110 1,444,191
Cash flows from financing activities:      
Net proceeds from issuances of common stock and exercise of options and warrants 548,475 3,583,038
Net cash provided by financing activities 548,475 3,583,038
Net (decrease) increase in cash and cash equivalents (4,020,707) (1,857,227) 1,703,414
Cash and cash equivalents at beginning of year 5,712,310 7,569,537 5,866,123
Cash and cash equivalents at end of year $ 1,691,603 $ 5,712,310 $ 7,569,537