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Consolidated Statement of Changes in Stockholders' Equity (USD $) | Total | Common Stock | Additional Paid-in Capital | Deficit Accumulated During the Development Stage
--- | --- | --- | --- | ---
Beginning Balance at Jun. 13, 2000 |  |  |  |
Issuance of founder shares | $ 30,000 | $ 9,990 | $ 20,010 |
Issuance of founder shares, Shares |  | 999,000 |  |
Proceeds from issuance of - stock | 1,750,000 | 1,457 | 1,748,543 |
Proceeds from issuance of - stock, Shares |  | 145,687 |  |
Net loss | (672,286) |  |  | (672,286)
Balance at Dec. 31, 2000 | 1,107,714 | 11,447 | 1,768,553 | (672,286)
Balance, Shares at Dec. 31, 2000 |  | 1,144,687 |  |
Proceeds from issuance of - stock | 2,250,000 | 1,873 | 2,248,127 |
Proceeds from issuance of - stock, Shares |  | 187,313 |  |
Net loss | (5,090,621) |  |  | (5,090,621)
Balance at Dec. 31, 2001 | (1,732,907) | 13,320 | 4,016,680 | (5,762,907)
Balance, Shares at Dec. 31, 2001 |  | 1,332,000 |  |
Proceeds from issuance of - stock | 3,250,000 | 1,804 | 3,248,196 |
Proceeds from issuance of - stock, Shares |  | 180,375 |  |
Net loss | (3,192,384) |  |  | (3,192,384)
Balance at Dec. 31, 2002 | (1,675,291) | 15,124 | 7,264,876 | (8,955,291)
Balance, Shares at Dec. 31, 2002 |  | 1,512,375 |  |
Proceeds from issuance of - stock | 6,781,250 | 2,090 | 6,779,160 |
Proceeds from issuance of - stock, Shares |  | 208,992 |  |
Net loss | (3,532,044) |  |  | (3,532,044)
Balance at Dec. 31, 2003 | 1,573,915 | 17,214 | 14,044,036 | (12,487,335)
Balance, Shares at Dec. 31, 2003 |  | 1,721,367 |  |
Proceeds from issuance of - stock | 4,600,000 | 7,659 | 4,592,341 |
Proceeds from issuance of - stock, Shares |  | 765,900 |  |
Net loss | (5,734,791) |  |  | (5,734,791)
Balance at Dec. 31, 2004 | 439,124 | 24,873 | 18,636,377 | (18,222,126)
Balance, Shares at Dec. 31, 2004 |  | 2,487,267 |  |
Proceeds from issuance of - stock | 3,900,000 | 6,494 | 3,893,506 |
Proceeds from issuance of - stock, Shares |  | 649,350 |  |
Option expense | 315,388 |  | 315,388 |
Net loss | (4,580,237) |  |  | (4,580,237)
Balance at Dec. 31, 2005 | 74,275 | 31,367 | 22,845,271 | (22,802,363)
Balance, Shares at Dec. 31, 2005 |  | 3,136,617 |  |
Proceeds from issuance of - stock | 7,550,541 | 8,390 | 7,542,151 |
Proceeds from issuance of - stock, Shares |  | 839,042 |  |
Option expense | 252,308 |  | 252,308 |
Net loss | (6,053,362) |  |  | (6,053,362)
Balance at Dec. 31, 2006 | 1,823,762 | 39,757 | 30,639,730 | (28,855,725)
Balance, Shares at Dec. 31, 2006 |  | 3,975,659 |  |
Proceeds from issuance of - stock | 6,600,000 | 7,326 | 6,592,674 |
Proceeds from issuance of - stock, Shares |  | 732,600 |  |
Common stock issued for services | 398,810 | 664 | 398,146 |
Common stock issued for services, Shares |  | 66,402 |  |
Option expense | 255,061 |  | 255,061 |
Net loss | (5,617,581) |  |  | (5,617,581)
Balance at Dec. 31, 2007 | 3,460,052 | 47,747 | 37,885,611 | (34,473,306)
Balance, Shares at Dec. 31, 2007 |  | 4,774,661 |  |
Proceeds from issuance of - stock | 6,000,000 | 9,990 | 5,990,010 |
Proceeds from issuance of - stock, Shares |  | 999,000 |  |
Option expense | 269,618 |  | 269,618 |
Net loss | (5,570,905) |  |  | (5,570,905)
Balance at Dec. 31, 2008 | 4,158,765 | 57,737 | 44,145,239 | (40,044,211)
Balance, Shares at Dec. 31, 2008 |  | 5,773,661 |  |
Option expense | 112,382 |  | 112,382 |
Net loss | (3,425,986) |  |  | (3,425,986)
Balance at Dec. 31, 2009 | 845,161 | 57,737 | 44,257,621 | (43,470,197)
Balance, Shares at Dec. 31, 2009 |  | 5,773,661 |  |
Option expense | 21,166 |  | 21,166 |
Net loss | (467,266) |  |  | (467,266)
Balance at Dec. 31, 2010 | 399,061 | 57,737 | 44,278,787 | (43,937,463)
Balance, Shares at Dec. 31, 2010 |  | 5,773,661 |  |
Proceeds from issuance of - stock | 5,379,367 | 78,911 | 5,300,456 |
Proceeds from issuance of - stock, Shares |  | 7,891,141 |  |
Option expense | 19,935 |  | 19,935 |
Warrant expense | 2,153,442 |  | 2,153,442 |
Fair value of derivative warrants | (3,887,850) |  | (3,887,850) |
Beneficial conversion feature discount | 372,850 |  | 372,850 |
Net loss | (3,444,795) |  |  | (3,444,795)
Balance at Dec. 31, 2011 | 992,010 | 136,648 | 48,237,620 | (47,382,258)
Balance, Shares at Dec. 31, 2011 |  | 13,664,802 |  |
Proceeds from issuance of - stock | 5,129,940 | 40,877 | 5,089,063 |
Proceeds from issuance of - stock, Shares |  | 4,087,747 |  |
Conversion of notes payable and accrued interest to stock | 981,729 | 12,525 | 969,204 |
Conversion of notes payable and accrued interest to stock, Shares |  | 1,252,550 |  |
Shares issued at the reverse merger |  | 23,866 | (23,866) |
Shares issued at the reverse merger, Shares |  | 2,386,566 |  |
Option expense | 266,172 |  | 266,172 |
Warrant expense | 1,957,754 |  | 1,957,754 |
Fair value of derivative warrants | (4,052,089) |  | (4,052,089) |
Transfer from liability classification to equity classification | 4,231,324 |  | 4,231,324 |
Net loss | (8,361,205) |  |  | (8,361,205)
Balance at Dec. 31, 2012 | $ (1,145,635) | $ 213,916 | $ 56,675,181 | $ (55,713,465)
Balance, Shares at Dec. 31, 2012 |  | 21,391,665 |  |

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