<SEC-DOCUMENT>0001213900-14-005334.txt : 20140804
<SEC-HEADER>0001213900-14-005334.hdr.sgml : 20140804
<ACCEPTANCE-DATETIME>20140804081613
ACCESSION NUMBER:		0001213900-14-005334
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20140804
ITEM INFORMATION:		Regulation FD Disclosure
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20140804
DATE AS OF CHANGE:		20140804

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Actinium Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001388320
		STANDARD INDUSTRIAL CLASSIFICATION:	BLANK CHECKS [6770]
		IRS NUMBER:				880378336
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36374
		FILM NUMBER:		141011543

	BUSINESS ADDRESS:	
		STREET 1:		501 FIFTH AVENUE, 3RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		212-300-2131

	MAIL ADDRESS:	
		STREET 1:		501 FIFTH AVENUE, 3RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cactus Ventures, Inc.
		DATE OF NAME CHANGE:	20070130
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>f8k080414_actiniumpharma.htm
<DESCRIPTION>CURRENT REPORT
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<P STYLE="margin-top: 0; margin-bottom: 0; text-align: center">&nbsp;</P>

<P STYLE="margin-top: 0; margin-bottom: 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>SECURITIES
AND EXCHANGE COMMISSION</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Washington,
D.C. 20549</B></FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>FORM
8-K</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>CURRENT
REPORT</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Pursuant
to Section 13 or 15(d) of the</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Securities
Exchange Act of 1934</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Date
of Report (Date of earliest event reported): August 4, 2014</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>ACTINIUM PHARMACEUTICALS, INC.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Exact name of registrant as specified in its
charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD STYLE="width: 30%; border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-size: 10pt"><b>Delaware</b></font></td>
    <TD STYLE="width: 3%; padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="width: 30%; border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-size: 10pt"><b>000-52446</b></font></td>
    <TD STYLE="width: 3%; padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="width: 34%; border-bottom: Black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-size: 10pt"><b>88-0378336</b></font></td></tr>
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    <TD STYLE="font: 10pt Times New Roman, Times, Serif">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(State or other jurisdiction</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">of&nbsp;incorporation)</P></td>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Commission</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">File Number)</P></td>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif">
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(IRS Employer</P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Identification No.)</P></td></tr>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><b>501 Fifth Avenue, 3rd Floor</b></P>
        <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><b>New York, NY</b></P></td>
    <TD STYLE="vertical-align: top; width: 2%; padding-bottom: 1.5pt; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="vertical-align: bottom; width: 49%; border-bottom: black 1.5pt solid; font: 10pt Times New Roman, Times, Serif; text-align: center"><font style="font-size: 10pt"><b>10017</b></font></td></tr>
<TR STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif"><font style="font-size: 10pt">(Address of principal executive offices)</font></td>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif"><font style="font-size: 10pt">(Zip Code)</font></td></tr>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">Registrant&rsquo;s telephone number, including
area code: <B>(646) 459-4201</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD STYLE="width: 100%; text-align: center; font: 10pt Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid"><font style="font-size: 10pt"><b>N/A</b></font></td></tr>
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    <TD STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif"><font style="font-size: 10pt">(Former name or former address, if changed since last report)</font></td></tr>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Check the appropriate box below if the Form 8-K filing is intended
to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (<U>see</U> General Instruction
A.2. below):</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

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    <TD STYLE="width: 94%; font: 10pt Times New Roman, Times, Serif; text-align: justify"><font style="font-size: 10pt">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</font></td></tr>
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    <TD STYLE="width: 94%; font: 10pt Times New Roman, Times, Serif; text-align: justify"><font style="font-size: 10pt">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a -12)</font></td></tr>
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    <TD STYLE="width: 94%; font: 10pt Times New Roman, Times, Serif; text-align: justify"><font style="font-size: 10pt">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d -2(b))</font></td></tr>
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    <TD STYLE="width: 94%; font: 10pt Times New Roman, Times, Serif; text-align: justify"><font style="font-size: 10pt">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e -4(c))</font></td></tr>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;&nbsp;</P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0"><B>Item 7.01 Regulation FD.</B></P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0; text-align: justify">Actinium Pharmaceuticals, Inc. issued a press release on August
4, 2014 providing a mid-year update to shareholders. A copy of the release is attached to this Form 8-K as Exhibit&nbsp;99.1.</P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0"><B>Item 9.01 Financial Statements and Exhibits.</B></P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0"><FONT STYLE="font-size: 10pt"><I>(d) Exhibits. </I></FONT><FONT STYLE="font-size: 7pt">&nbsp;</FONT></P>

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    <TD STYLE="padding: 0.7pt; font: 10pt Times New Roman, Times, Serif; width: 9%"><font style="font-size: 10pt">Exhibit&nbsp;99.1</font></td>
    <TD STYLE="padding: 0.7pt; font: 10pt Times New Roman, Times, Serif; width: 1%">&nbsp;</td>
    <TD STYLE="padding: 0.7pt; font: 10pt Times New Roman, Times, Serif; width: 90%; text-align: justify"><font style="font-size: 10pt">Press release of Actinium Pharmaceuticals, Inc., dated August 4, 2014</font></td></tr>
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<P STYLE="font: 10pt/120% Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><font style="font-size: 10pt">Dated: August 4, 2014</font></td>
    <TD COLSPAN="3" STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="font-size: 10pt"><B>ACTINIUM PHARMACEUTICALS, INC.</B></FONT></td></tr>
<TR STYLE="font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="vertical-align: top; width: 58%; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="width: 5%; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="width: 27%; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="width: 10%; font: 10pt Times New Roman, Times, Serif">&nbsp;</td></tr>
<TR STYLE="font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</td>
    <TD STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif"><font style="font-size: 10pt">By:</font></td>
    <TD STYLE="vertical-align: bottom; font: 10pt Times New Roman, Times, Serif; border-bottom: Black 1.5pt solid"><font style="font-size: 10pt"><i>/s/ Kaushik J. Dave&nbsp;</i></font></td>
    <TD STYLE="vertical-align: bottom; font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</td></tr>
<TR STYLE="font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif">Name:</TD>
    <TD STYLE="vertical-align: bottom; font: 10pt Times New Roman, Times, Serif">Kaushik J. Dave</TD>
    <TD STYLE="vertical-align: bottom; font: 10pt Times New Roman, Times, Serif; padding-bottom: 1.5pt">&nbsp;</TD></TR>
<TR STYLE="font: 10pt Times New Roman, Times, Serif">
    <TD STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif">&nbsp;</td>
    <TD STYLE="vertical-align: top; font: 10pt Times New Roman, Times, Serif">Title:</td>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; font: 10pt Times New Roman, Times, Serif"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0pt">President and Chief Executive Officer</P>

</td></tr>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0; text-align: center; margin-bottom: 0">3</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-indent: 0.5in"></P>

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<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>f8k080414ex99i_actinium.htm
<DESCRIPTION>PRESS RELEASE
<TEXT>
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<P STYLE="margin-top: 0; text-align: right; margin-bottom: 0"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Exhibit
99.1</B></FONT></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin-top: 0; text-align: center; margin-bottom: 0">&nbsp;<IMG SRC="img01.jpg" ALT=""></P>

<P STYLE="margin-top: 0; text-align: center; margin-bottom: 0"><FONT STYLE="font-size: 12pt"><B>Actinium Pharmaceuticals, Inc.</B></FONT></P>

<P STYLE="margin: 0"></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0"></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>ACTINIUM
PHARMACEUTICALS PROVIDES MID-YEAR UPDATE DIRECTED AT EXISTING AND FUTURE SHAREHOLDERS</B></FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><I>Material
Progress On All Fronts To Date in 2014 &ndash; Including: Pipeline Advances, Improved Stock Market Profile, Stronger Balance Sheet,
Fortified Executive Team and Strong Support from Prominent Scientific Leaders &ndash; Leave Company Well Positioned To Capitalize
on The Promise of its Product Candidates&nbsp;</I></FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">NEW
YORK, NY &ndash; August 4, 2014 - <U>Actinium Pharmaceuticals, Inc.</U> (NYSE MKT: ATNM) (&quot;Actinium&quot; or &quot;the Company&quot;),
a biopharmaceutical company developing innovative targeted payload immunotherapeutics for the treatment of advanced cancers, today
provided a Mid-Year Corporate Update to new and existing shareholders. The highlights below underscore the significant progress
that the Company has achieved on all material fronts this year which leave it well positioned to execute on its business plan
and capitalize on the near-term promise of its core product candidates Iomab&trade;-B and Actimab-A.</FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B><U>Key
Achievements in 2014 </U></B></FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Enhanced
Stock Market Profile with NYSE Markets Uplisting, Addition to the Russell&reg; Indexes and Greater Trading Volume</B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Attracted
                                         Additional Research Analyst Coverage</B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Fortified
                                         Company Infrastructure with Key Executive Hires</B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Progression
                                         of Iomab&trade;-B towards Phase 3 Clinical Trial</B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>High-Profile
Visibility and Support for Iomab&trade;-B by Leading Expert</B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Advanced
Actimab-A Phase 1/2 Program</B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Initiated
                                         Support for Third Development Program </B></FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Strengthened
                                         Balance Sheet </B></FONT></TD></TR></TABLE>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&ldquo;Our
team wishes to thank our existing shareholders for their faith in Actinium this year.&rdquo; stated Kaushik J. Dave, Ph.D., President
and Chief Executive Officer. &ldquo;As can be clearly seen from the highlights of our achievements listed above and elucidated
below, we have made great progress since our shareholder update in December 2013. However, we are acutely aware that delivering
on our primary objectives of bringing Iomab&trade;-B to market in 2017 and establishing the clinical validity of Actimab-A for
the treatment of Acute Myeloid Leukemia (AML), requires us to meet nearer-term milestones on time. I assure you that our entire
team is energized and completely focused on meeting our corporate objectives&rdquo;.</FONT></P>

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<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 12pt 0; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B><U>ACHIEVEMENTS
AND HIGHLIGHTS FOR 2014 YTD</U>&nbsp;</B></FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Enhanced
                                         Stock Market Profile with NYSE Markets Uplisting, Addition to the Russell&reg; Indexes,
                                         Greater Trading Volume Coverage and Research Analyst Coverage</B></FONT></TD></TR></TABLE>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin-right: 0; margin-left: 0.5in; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">We
successfully uplisted from the OTC bulletin board to the NYSE-MKT, a national exchange, in March 2014. This action enables a broader
base of potential investors to invest in our strong future. We were privileged to join the broad-market Russell 3000&reg; Index
as well as the Russell 2000&reg;, Russell Global and Russell Microcap&reg; on June 27, 2014. <I>These exchange and index inclusions
coupled with our investor outreach efforts have resulted in greater than 12x improvement in liquidity (3-month average daily trading
volume) since the last shareholder update in December 2013.</I> Additional equity research coverage was initiated in July 2014
by Canaccord Genuity and featured a favorable rating and outlook for Actinium along the same line as the views of the existing
Laidlaw analyst. We continue to extend our outreach efforts to buy and sell-side research analysts and portfolio managers in order
to gain greater visibility and research coverage. We believe that our efforts should result in greater liquidity for our existing
shareholders as appreciation of Actinium&rsquo;s prospects with a wider audience takes hold and investor purchases increase.&nbsp;&nbsp;</FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">

<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><b>&#9679;<U></U></B> <FONT STYLE="font: 10pt Times New Roman, Times, Serif"></FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Strengthened Balance Sheet and Fortified Company Infrastructure with Key Executive Hires</B></FONT></TD></TR></TABLE>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"></FONT></P>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin-right: 0; margin-left: 0.5in; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">We
completed an underwritten secondary offering in June of 2014 which provided us $13.7 million and sufficient additional capital
to fund our accelerated development activities with Iomab&trade;-B and expand our clinical trial of Actimab-A for which we expect
to release interim results by year-end. <I>The strengthened balance sheet leaves the company with sufficient capital resources
to meet our major near-term milestones which is of great comfort.</I> Equally important, the potential inherent in our technology
platform and core Iomab&trade;-B and Actimab-A programs is further validated by our ability to attract top caliber, senior executives,
each with more than 20-years of experience and prior success in the healthcare industry. The Team will play a critical role in
ensuring that we meet or exceed our objectives across all key areas including Clinical Operations, Regulatory and Quality, Development,
Investor and Public Relations, and Business Development.&nbsp;</FONT></P>

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<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Advanced
                                         Iomab&trade;-B towards Phase 3 Clinical Trial</B></FONT></TD></TR></TABLE>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt 0.5in; padding: 0; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Iomab&trade;-B,
the Company&rsquo;s lead radioimmunotherapy asset, is on the cusp of entering a Pivotal Phase 3 trial to potentially address the
significant unmet medical need for older patients who require less toxic conditioning prior to a bone marrow transplant. Since
the last shareholder update, we have executed an agreement with ACT Oncology, a full-service, oncology focused, clinical research
organization, to help us prepare and execute the Phase 3 clinical trial of Iomab&trade;-B. We have started preparations for the
trial, including centers recruitment feasibility study and outreach. In addition, we have worked diligently to put in place strong
partners to ensure the highest quality manufacturing, labeling, and distribution of Iomab&trade;-B to support both the clinical
trial and potential commercialization. The necessary scale-up and validation for both the mAb and Iomab&trade;-B finished drug
product are currently at an advanced stage. Iomab&trade;-B is a complex program and therefore we are making sure that we address
all the requirements for not only a successful pivotal clinical study but also to ensure rapid regulatory approval and support
commercial launch.</FONT></P>

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<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; text-align: justify"></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt/107% Calibri, Helvetica, Sans-Serif"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><U></U> <FONT STYLE="font: 10pt Times New Roman, Times, Serif">&#9679;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>High-Profile
                                         Visibility and Support for Iomab&trade;-B with Leading Experts </B></FONT></TD></TR></TABLE>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 0 0.5in; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 0 0.5in; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">We
are pleased to report to our shareholders that the proof of concept data for Iomab&trade;-B and the significant medical advance
this drug candidate represents has attracted tremendous support from the thought leaders in bone marrow transplant. We are very
pleased to be able to showcase their enthusiastic endorsement of Iomab&trade;-B and our plans in a short three minute video we
have posted on our web site<B> </B>entitled<I> &ldquo;<U>Highlights from NY BIO Panel Discussion</U>&rdquo;<B>. </B></I> Please
do take a look. We are humbled that we have been provided with the fantastic opportunity to be part of the development process
that will bring such a lifesaving drug to patients who currently have no treatment options. In doing so, we will be well advised
and supported by our recently constituted Iomab&trade;-B Scientific Advisory Board which includes luminaries from some of the
most prestigious cancer and transplant centers including: the Fred Hutchinson Cancer Research Center, Memorial Sloan Kettering
Cancer Center, Case Western Reserve University, the Colorado Blood Cancer Institute, and Baylor Research Institute. This high-profile
visibility and support is expected to significantly influence the medical community and enable Actinium to develop Iomab&trade;-B
to the fullest extent of its potential in AML and in several other blood cancers where it has shown promise.</FONT></P>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 0 0.5in; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>&nbsp;</B></FONT></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt/107% Calibri, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 12pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in">&#9679;</TD><TD STYLE="text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Advanced
                                         Actimab-A Phase 1/2 Program and Initiated Support for a Third Development Program </B></FONT></TD></TR></TABLE>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt 0.5in; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">We
continue to march forward with the Actimab-A Phase 1/2<B> </B>trial and are on target to reveal interim results in December by
the annual meeting of the American Society of Hematology, the preeminent scientific society for blood cancer research. We recently
added Baylor Charles A. Sammons Cancer Center, one of the largest oncology centers in the nation treating over 55,000 cancer patients
every year, as a clinical trial site. They join several top US cancer centers including Memorial Sloan Kettering Cancer Center,
MD Anderson Cancer Center, Fred Hutchinson Cancer Research Center, Johns Hopkins Medicine and University of Pennsylvania Health
System. The addition of Baylor and other leading cancer centers with which we are in active discussions to join in the near future
will support the ongoing enrolment in our Phase 1/2 study. Separately, we recently announced the development of another antibody-actinium-225
labeled construct to support a third clinical program at Memorial Sloan Kettering Cancer Center and will look to advance select
additional programs where we already have a significant amount of both clinical and preclinical data.</FONT></P>

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<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt 0.5in; text-align: justify"></P>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&ldquo;As
plainly demonstrated above, we have been extremely busy this year executing on our plans to deliver on the business plan for both
the near-term and longer-term&rdquo;, stated Dr. Dave, &ldquo;In the near-term, we expect to release interim results on the Actimab-A
trial in December and to begin the Iomab&trade;-B trial in the first half of 2015. Longer-term, we expect to deliver on our primary
objectives of bringing Iomab&trade;-B to market in 2017 and establishing the clinical validity of Actimab-A, as we seek to build
an advanced, world-class oncology company that can address challenges of many types of cancer. We are confident our technologies
can provide us with many potentially first-in-class drugs to address unmet medical needs&rdquo;.</FONT></P>

<P STYLE="font: 10pt/107% Arial, Helvetica, Sans-Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">&ldquo;In
conclusion,&rdquo; stated Dr. Dave, &ldquo;we are proud to report to our shareholders that Team Actinium has made material progress
on all fronts to date in 2014 including: pipeline advances, a much improved stock market profile, a stronger balance sheet, a
fortified executive team and high-profile support from prominent scientific leaders. This progress, dear shareholders, leaves
your company well-positioned to capitalize on the promise of its product candidates to deliver value. We thank-you once again
for your support and hope that you will be with us to share our future successes.&rdquo;</FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 12pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>About Actinium Pharmaceuticals</B></FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Actinium
Pharmaceuticals, Inc. (<U>www.actiniumpharma.com</U>) is a New York-based biopharmaceutical company developing innovative targeted
payload immunotherapeutics for the treatment of advanced cancers. Actinium's targeted radiotherapy is based on its proprietary
delivery platform for the therapeutic utilization of alpha-emitting actinium-225 and bismuth-213 and certain beta-emitting radiopharmaceuticals
in conjunction with monoclonal antibodies. The Company&rsquo;s lead radiopharmaceutical Iomab&trade;-B will be used in preparing
patients for hematopoietic stem cell transplant, commonly referred to as bone marrow transplant. The Company is preparing a single,
pivotal, multicenter Phase 3 clinical study of Iomab&trade;-B in refractory and relapsed Acute Myeloid Leukemia (AML) patients
over the age of 55 with a primary endpoint of durable complete remission. The Company&rsquo;s second program, Actimab-A, is continuing
its clinical development in a Phase 1/2 trial for newly diagnosed AML patients over the age of 60 in a single-arm multicenter
trial.</FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Forward-Looking
Statement for Actinium Pharmaceuticals, Inc.</B></FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">This
news release contains &ldquo;forward-looking statements&rdquo; as defined in the Private Securities Litigation Reform Act of 1995.
These statements are based on management's current expectations and involve risks and uncertainties, which may cause actual results
to differ materially from those set forth in the statements. The forward-looking statements may include statements regarding product
development, product potential, or financial performance. No forward-looking statement can be guaranteed and actual results may
differ materially from those projected. Actinium Pharmaceuticals undertakes no obligation to publicly update any forward-looking
statement, whether as a result of new information, future events, or otherwise.</FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><B>Contact:</B></FONT></P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt; text-align: justify"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Actinium
Pharmaceuticals, Inc. Evan Smith, CFA, VP Investor Relations and Finance, +1 (646) 840-5442, Email: <FONT STYLE="color: Black"><U>esmith@actiniumpharma.com</U></FONT></FONT>&nbsp;</P>

<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin-top: 0; margin-bottom: 8pt; text-align: center"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">4</FONT></P>

<HR NOSHADE STYLE="color: Black; width: 100%; height: 1.5pt; margin-top: 0pt; margin-bottom: 0pt">
<P STYLE="font: 12pt/107% Arial, Helvetica, Sans-Serif; margin: 0 0 8pt"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"><FONT STYLE="color: Black">&nbsp;</FONT></FONT></P>

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`
end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
