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v3.3.1.900

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Cash Flows From Operating Activities: |  |  |
Net loss | $ (21,025,314) | $ (24,687,509) | $ (10,773,792)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: |  |  |
Stock-based compensation expense | 7,061,622 | 6,280,629 | 657,812
Depreciation expense | $ 53,465 | $ 37,908 | 1,560
Loss on disposition of equipment |  |  | 4,122
Loss (gain) on change in fair value of derivative liabilities | $ (3,812,318) | $ 2,206,099 | 4,179,392
(Increase) decrease in: |  |  |
Prepaid expenses and other current assets | 162,083 | (193,894) | 106,579
Increase (decrease) in: |  |  |
Accounts payable and accrued expenses | (793,949) | 1,874,841 | (518,089)
Accounts payable and accrued expenses - related party | (189,357) | 133,172 | 50,000
Net Cash Used In Operating Activities | $ (18,543,768) | (14,348,754) | $ (6,292,416)
Cash Flows From Investing Activities: |  |  |
Restricted cash |  | (34,733) |
Purchase of property and equipment | $ (47,788) | (151,688) | $ (16,592)
Net Cash Used In Investing Activities | (47,788) | (186,421) | (16,592)
Cash Flows From Financing Activities: |  |  |
Payments on note payable | (283,552) | (161,841) | (140,000)
Sales of stock, net of offering costs | 37,637,959 | 15,435,305 | 2,883,257
Proceeds from the exercise of options | 15,680 | 275,153 | 13,053
Proceeds from the exercise of warrants | 157,940 | 159,994 | 3,467,395
Net Cash Provided By Financing Activities | 37,528,027 | 15,708,611 | 6,223,705
Net change in cash | 18,936,471 | 1,173,436 | (85,303)
Cash at beginning of year | 6,706,802 | 5,533,366 | 5,618,669
Cash at end of year | 25,643,273 | 6,706,802 | 5,533,366
Supplemental disclosures of cash flow information: |  |  |
Cash paid for interest | $ 7,868 | $ 866 | $ 561
Cash paid for taxes |  |  |
Supplemental disclosure of non-cash investing and financing activities: |  |  |
Stock issuance costs included in accounts payable and accrued expenses |  | $ 30,000 |
Insurance prepaid through premium finance | $ 265,695 | $ 287,568 | $ 157,825
Fair value of warrants issued with stock | 4,738,161 |  |
Transfer from derivative liability classification to equity classification | $ 48,691 | $ 2,203,443 | $ 1,047,095

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