<SEC-DOCUMENT>0001213900-16-019419.txt : 20161214
<SEC-HEADER>0001213900-16-019419.hdr.sgml : 20161214
<ACCEPTANCE-DATETIME>20161214171125
ACCESSION NUMBER:		0001213900-16-019419
CONFORMED SUBMISSION TYPE:	DEFA14A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20161214
DATE AS OF CHANGE:		20161214
EFFECTIVENESS DATE:		20161214

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Actinium Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001388320
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				880378336
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEFA14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36374
		FILM NUMBER:		162051761

	BUSINESS ADDRESS:	
		STREET 1:		275 MADISON AVENUE, 7TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016
		BUSINESS PHONE:		646-677-3875

	MAIL ADDRESS:	
		STREET 1:		275 MADISON AVENUE, 7TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cactus Ventures, Inc.
		DATE OF NAME CHANGE:	20070130
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEFA14A
<SEQUENCE>1
<FILENAME>defa14a1216_actinium.htm
<DESCRIPTION>DEFINITIVE ADDITIONAL MATERIALS
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<P STYLE="border-top: Black 6pt double; font: 10pt/12pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><BR><FONT STYLE="font-weight: normal">UNITED
STATES</FONT><BR>
<FONT STYLE="font-weight: normal">SECURITIES AND EXCHANGE COMMISSION</FONT><BR>
<FONT STYLE="font-weight: normal">Washington, D.C. 20549</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-weight: normal">______________________</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 9pt 0 0; text-align: center"><FONT STYLE="font-weight: normal">SCHEDULE
14A</FONT><BR>
<FONT STYLE="font-weight: normal">Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934</FONT><BR>
<FONT STYLE="font-weight: normal">(Amendment No. &#8199;&#8199;)</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0; text-align: center"><FONT STYLE="font-weight: normal">______________________</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 8pt 0 0">Filed by the Registrant <FONT STYLE="font-family: Wingdings">x</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 6pt 0 0">Filed by a Party other than the Registrant <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 6pt 0 10pt">Check the appropriate box:</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD STYLE="width: 96%; line-height: 11pt">Preliminary Proxy Statement</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD STYLE="line-height: 11pt">Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))&nbsp;&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD STYLE="line-height: 11pt">Definitive Proxy Statement</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">x</FONT></TD>
    <TD STYLE="line-height: 11pt">Definitive Additional Materials</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD STYLE="line-height: 11pt">Soliciting Material under Rule 14a-12</TD></TR>
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<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 10pt 0 0; text-align: center"><FONT STYLE="font-weight: normal">Actinium
Pharmaceuticals, Inc.</FONT></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Name of Registrant as Specified In Its
Charter)</P>

<P STYLE="font: bold 10pt/12pt Times New Roman, Times, Serif; margin: 4pt 0 0; text-align: center">N/A</P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 3pt 0 0; text-align: center">(Name of Person(s) Filing Proxy Statement,
if other than the Registrant)</P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 6pt 0 10pt">Payment of Filing Fee (Check the appropriate box):</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">x</FONT></TD>
    <TD COLSPAN="2" STYLE="line-height: 11pt">No fee required.</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="width: 5%; font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="width: 90%; font-size: 12pt; line-height: 120%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD COLSPAN="2" STYLE="line-height: 11pt">Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">1.</TD>
    <TD STYLE="line-height: 11pt">Title of each class of securities to which transaction applies:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">2.</TD>
    <TD STYLE="line-height: 11pt">Aggregate number of securities to which transaction applies:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">3.</TD>
    <TD STYLE="line-height: 11pt">Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the filing fee is calculated and state how it was determined):</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">4.</TD>
    <TD STYLE="line-height: 11pt">Proposed maximum aggregate value of transaction:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">5.</TD>
    <TD STYLE="line-height: 11pt">Total fee paid:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD COLSPAN="2" STYLE="line-height: 11pt">Fee paid previously with preliminary materials.</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="line-height: 11pt"><FONT STYLE="font-family: Wingdings">&uml;</FONT></TD>
    <TD COLSPAN="2" STYLE="line-height: 11pt">Check box if any part of the fee is offset as provided by Exchange Act Rule 0-1 1(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">1.</TD>
    <TD STYLE="line-height: 11pt">Amount Previously Paid:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">2.</TD>
    <TD STYLE="line-height: 11pt">Form, Schedule or Registration Statement No.:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">3.</TD>
    <TD STYLE="line-height: 11pt">Filing Party:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="line-height: 11pt">4.</TD>
    <TD STYLE="line-height: 11pt">Date Filed:</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="font-size: 12pt; line-height: 120%">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; line-height: 10pt">&nbsp;</TD></TR>
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<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 10pt 0 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 10pt 0 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>EXPLANATORY NOTE </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Actinium Pharmaceuticals, Inc. (the &ldquo;Company&rdquo;)
is providing shareholders with updated information relating to its nomination of directors on page 10 of the Company&rsquo;s Proxy
Statement filed on November 18, 2016.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0"><B><I>Nomination of Directors</I></B></P>

<P STYLE="font: 10pt/12pt Times New Roman, Times, Serif; margin: 8pt 0 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Board
of Director nominations are selected, or recommended for the Board&rsquo;s selection, by a majority of the independent directors.
</FONT>Our independent directors include David Nicholson, Richard I. Steinhart and Sergio Traversa. These directors are charged
with the responsibility of proposing potential director nominees to the board of directors for consideration. All of our independent
directors are independent directors as defined by the rules of the NYSE MKT. Our independent directors uses criteria by which it will seek to evaluate
candidates to serve on our board of directors. The evaluation methodology includes items such as experience in the biotechnology
sector, experience with public companies, executive managerial experience, operations and commercial experience, fundraising experience
and contacts in the investment banking industry, personal and skill set compatibility with current board members, industry reputation,
knowledge of our company generally, and independence.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>&nbsp;</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I>This supplement should be considered in
conjunction with the Proxy Statement.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify"><I></I></P>

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