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Income Taxes (Details Textual) - USD ($) | 12 Months Ended
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Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Income Taxes (Textual) |  |  |
Deferred tax assets, valuation allowance | $ 47,802,380 | $ 28,910,183 |
U.S. Federal statutory rate | (34.00%) | (34.00%) | (34.00%)
Domestic Tax Authority [Member] |  |  |
Income Taxes (Textual) |  |  |
Net operating losses | $ 105,100,000 |  |
Net operating loss expiration date | Dec. 31, 2018 |  |
Domestic Tax Authority [Member] | Research Tax Credit Carryforward [Member] |  |  |
Income Taxes (Textual) |  |  |
Net operating losses | $ 830,000 |  |
Net operating loss expiration date | Dec. 31, 2033 |  |
State and Local Jurisdiction [Member] |  |  |
Income Taxes (Textual) |  |  |
Net operating losses | $ 60,700,000 |  |
Net operating loss expiration date | Dec. 31, 2035 |  |

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