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Income Taxes (Details 1) - USD ($) | 12 Months Ended
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Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
schedule of difference between income tax provision and U.S federal statutory rate |  |  |
Federal income taxes at 34% | $ (8,269,386) | $ (7,148,607) | $ (8,393,753)
Federal income taxes at 34%, percentage | (34.00%) | (34.00%) | (34.00%)
Deferred true-up | $ (5,946,655) | $ 1,104,763 | $ 2,885,487
Deferred true-up, percentage | $ (24.45) | $ 5.25 | $ 11.69
Research and Development Tax Credit | $ (141,769) |  |
Research and Development Tax Credit, percentage | (0.58%) |  |
Unrealized derivative gain/loss | $ (860,460) |  |
Unrealized derivative gain/loss, percentage | (3.54%) |  |
Other | $ 12,259 |  | $ 526,224
Other, percentage | 0.05% |  | 2.13%
Change in valuation allowance | $ 15,206,011 | $ 6,043,844 | $ 4,982,042
Change in valuation allowance, percentage | 62.52% | 28.75% | 20.18%
Provision for income tax |  |  |
Provision for income tax, percent |  |  |

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