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Consolidated Statements of Operations (Unaudited) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Statements of Operations [Abstract]        
Revenue
Operating expenses:        
Research and development, net of reimbursements 4,379,047 4,147,945 8,883,398 7,913,397
General and administrative 2,809,918 2,750,448 6,090,235 4,968,915
Depreciation expense 14,335 19,472 35,255 37,592
Total operating expenses 7,203,300 6,917,865 15,008,888 12,919,904
Loss from operations (7,203,300) (6,917,865) (15,008,888) (12,919,904)
Other income (expense):        
Interest expense (1,683) (4,341)
Gain (loss) on change in fair value of derivative liabilities 149,592 295,462 (106,403) 1,896,861
Total other income (expense) 149,592 293,779 (106,403) 1,892,520
Net loss $ (7,053,708) $ (6,624,086) $ (15,115,291) $ (11,027,384)
Net loss per common share - basic and diluted $ (0.12) $ (0.14) $ (0.26) $ (0.24)
Weighted average common shares outstanding - basic and diluted 58,184,534 46,470,225 57,045,036 45,362,009