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Commitments and Contingencies (Details Textual) - USD ($) |  |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Dec. 13, 2017 | Jun. 08, 2017 | Aug. 04, 2016 | Jun. 15, 2012 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
Rent for office |  | $ 7,529 |  |  |  |  |
Incurred expenses |  |  |  |  | $ 17,699,503 | $ 17,786,655 | $ 13,501,895
Cost of lease agreement |  |  |  |  | 312,660 |  |
Accounts payable and accrued expenses |  |  |  |  | $ 4,625,088 | 4,194,874 |
Lease agreements, description |  |  |  |  | The lease expires September 6, 2024 with an annual rental rate of $312,660 per year through June 6, 2021 and an annual rate of $341,610 for the remaining period. |  |
Lines of credit |  |  |  |  | $ 390,825 |  |
Deposit |  |  |  |  | 390,940 |  |
Fred Hutchinson Cancer Research Center [Member] |  |  |  |  |  |  |
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
Milestones Payments |  |  |  | $ 1,000,000 |  |  |
Description of royalty payment |  |  |  | Royalty payments of 2% of net sales will be due to FHCRC. |  |  |
Incurred expenses |  |  |  |  | 45,000 |  |
Medpace Inc [Member] |  |  |  |  |  |  |
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
Incurred expenses |  |  |  |  | 2,800,000 | 2,600,000 |
Total project estimated to cost |  |  |  |  | 7,200,000 |  |
Oak Ridge National Laboratory [Member] |  |  |  |  |  |  |
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
Purchase of materials | $ 2,000,000 |  |  |  | 600,000 | 1,000,000 | 800,000
George Clinical Services [Member] |  |  |  |  |  |  |
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
Project estimated cost |  |  | $ 4,600,000 |  | 700,000 | 100,000 |
Goodwin Biotechnology Inc [Member] |  |  |  |  |  |  |
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
Project remaining cost |  |  |  |  | 1,800,000 |  |
Incurred expenses |  |  |  |  | 4,200,000 | $ 700,000 | $ 1,400,000
Product Development and Patent License Agreement [Member] | AbbVie Biotherapeutics Corp. [Member] |  |  |  |  |  |  |
Commitments and Contingencies (Textual) |  |  |  |  |  |  |
License fee payment |  |  |  |  | $ 3,000,000 |  |
Description of royalty payment |  |  |  |  | The Company shall pay to AbbVie Biotherapeutics Corp. on a country-by-country basis a royalty of 12% of net sales of all licensed products until the later of: (1) 12.5 years after the first commercial sale, or (2) when the patents expire. |  |
Royalty of net sales percentage |  |  |  |  | 12.00% |  |
First commercial sale period |  |  |  |  | 12 years 6 months |  |
Accounts payable and accrued expenses |  |  |  |  | $ 750,000 |  |

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