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Description of Business and Summary of Significant Accounting Policies (Details Textual) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Description of Business and Summary of Significant Accounting Policies (Textual)
Federal corporate tax rate	21.00%	34.00%	34.00%
Net loss	$ (23,653,963)	$ (26,601,235)	$ (24,321,724)
Net cash used in operations	(20,571,056)	(21,553,346)	(20,789,237)
Cash and cash equivalents	13,673,308	17,399,636	$ 20,519,294
Accumulated deficit	$ (186,857,238)	$ (163,153,037)
Minimum [Member]
Description of Business and Summary of Significant Accounting Policies (Textual)
Federal corporate tax rate		35.00%
Maximum [Member]
Description of Business and Summary of Significant Accounting Policies (Textual)
Federal corporate tax rate		21.00%
Furniture and Fixtures [Member]
Description of Business and Summary of Significant Accounting Policies (Textual)
Estimated useful lives, description	Seven years
Property and equipment depreciation method	Straight-line basis
Machinery and Equipment [Member]
Description of Business and Summary of Significant Accounting Policies (Textual)
Estimated useful lives, description	Three to five years
Property and equipment depreciation method	Straight-line basis

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Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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