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Description of Business and Summary of Significant Accounting Policies (Tables)
 3 Months Ended
Mar. 31, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Summary of cash and cash equivalent and restricted cash
   March 31,
2019		   December 31,
2018		 
Cash and cash equivalents  $9,924,882   $13,673,308 
Restricted cash – current   40,105    40,075 
Restricted cash – long term   391,180    391,131 
Cash, cash equivalent and restricted cash  $10,356,167   $14,104,514 
Schedule of antidilutive securities excluded from computation of diluted net loss per share
   March 31,
2019		   March 31, 2018 
Options   7,783,301    5,812,042 
Warrants   43,473,269    55,903,878 
Total   51,256,570    61,715,920