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Income Taxes (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020
Income Taxes (Details) [Line Items] |  |
Deferred tax assets, valuation allowance | $ 62.6 | $ 56.2
Federal income tax purposes, net operating losses | $ 163.0 |
Net operating losses, description | NOLs of $120.8 million generated prior to 2018 will begin to expire if unused in 2022. NOLs generated in 2018 and later years of $42.2 million have an indefinite life, but will be limited to 80% of their value if used in a tax year ending after January 1, 2022. |
State income tax purposes, net operating losses |  | $ 87.9
Federal Research and Development Tax Credits [Member] |  |
Income Taxes (Details) [Line Items] |  |
Net operating loss expiration date | The Company has federal research and development tax credits of $2.9 million at December 31, 2021 which will begin to expire in 2034 if unused and orphan drug credits of $11.6 million which will begin to expire in 2028 if unused. |
Net operating losses | $ 2.9 |
Orphan Drug Credits [Member] |  |
Income Taxes (Details) [Line Items] |  |
Net operating losses | $ 11.6 |

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